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Title: | Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial |
Author: | Sánchez-Villegas, Almudena Alvarez Pérez, Jacqueline Toledo Atucha, Estefanía Salas Salvadó, Jordi Ortega Azorín, Carolina Zomeño Fajardo, María Dolores Vioque, Jesús Martínez, J. Alfredo, 1957- Romaguera, Dora Pérez López, Jessica López Miranda, José Estruch Riba, Ramon Bueno Cavanillas, Aurora Arós, Fernando Tur, Josep Antoni Tinahones, Francisco J. Lecea, Oscar Martín Sánchez, Vicente Ortega Calvo, Manuel Vázquez, Clotilde Pintó Sala, Xavier Vidal i Cortada, Josep Daimiel, Lidia Delgado Rodríguez, Miguel Matía Martín, Pilar Corella Piquer, Dolores Díaz López, Andrés Babio, Nancy Muñoz, Miguel Ángel Fitó Colomer, Montserrat García de la Hera, Manuela Abete, Itziar García Ríos, Antonio Ros Rahola, Emilio Ruiz Canela, Miguel Martínez-González, Miguel Ángel, 1957- Izquierdo, Marisol Serra Majem, Lluís |
Keywords: | Assaigs clínics Depressió psíquica Àcids grassos omega-3 Dietoteràpia Clinical trials Mental depression Omega-3 fatty acids Diet therapy |
Issue Date: | 18-Dec-2018 |
Publisher: | MDPI |
Abstract: | BACKGROUND: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (ω-3 PUFA) intake, and depression prevalence. METHODS: Cross-sectional analyses of the PREDIMED-Plus trial. Fish and seafood consumption and ω-3 PUFA intake were assessed through a validated food-frequency questionnaire. Self-reported life-time medical diagnosis of depression or use of antidepressants was considered as outcome. Depressive symptoms were collected by the Beck Depression Inventory-II. Logistic regression models were used to estimate the association between seafood products and ω-3 PUFA consumption and depression. Multiple linear regression models were fitted to assess the association between fish and long-chain (LC) ω-3 PUFA intake and depressive symptoms. RESULTS: Out of 6587 participants, there were 1367 cases of depression. Total seafood consumption was not associated with depression. The odds ratios (ORs) (95% confidence intervals (CIs)) for the 2nd, 3rd, and 4th quintiles of consumption of fatty fish were 0.77 (0.63⁻0.94), 0.71 (0.58⁻0.87), and 0.78 (0.64⁻0.96), respectively, and p for trend = 0.759. Moderate intake of total LC ω-3 PUFA (approximately 0.5⁻1 g/day) was significantly associated with a lower prevalence of depression. CONCLUSION: In our study, moderate fish and LC ω-3 PUFA intake, but not high intake, was associated with lower odds of depression suggesting a U-shaped relationship. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/nu10122000 |
It is part of: | Nutrients, 2018, vol. 10, num. 12, p. pii: E2000 |
URI: | http://hdl.handle.net/2445/157577 |
Related resource: | https://doi.org/10.3390/nu10122000 |
ISSN: | 2072-6643 |
Appears in Collections: | Articles publicats en revistes (Medicina) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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