Please use this identifier to cite or link to this item:
Title: Ultra-trace analysis of cyanotoxins by liquid chromatography coupled to high-resolution mass spectrometry
Author: Filatova, Daria
Núñez Burcio, Oscar
Farré, Marinella
Keywords: Cromatografia de líquids
Toxines bacterianes
Liquid chromatography
Bacterial toxins
Issue Date: 7-Apr-2020
Publisher: MDPI
Abstract: The increasing frequency of episodes of harmful algal blooms of cyanobacterial origin is a risk for ecosystems and human health. The main human hazard may arise from drinking water supply and recreational water use. For this reason, efficient multiclass analytical methods are needed to assess the level of cyanotoxins in water reservoirs and tackle these problems. This work describes the development of a fast, sensitive and robust analytical method for multiclass cyanotoxins determination based on dual solid-phase extraction (SPE) procedure using a polymeric cartridge first Oasis HLB (Waters Corporation, USA), and second, a graphitized non-porous carbon cartridge, SupelcleanTM ENVI-CarbTM (Sigma-Aldrich, USA), followed by ultra-high performance liquid chromatography high-resolution mass spectrometry (SPE-UHPLC-HRMS). This method enabled the analysis of cylindrospermopsin, anatoxin-a, nodularin and seven microcystins (MC-LR, MC-RR, MC-YR, MC-LA, MC-LY, MC-LW, MC-LF). The method limits of detection (MLOD) of the validated approach were between 4 and 150 pg/L. The analytical method was applied to assess the presence of the selected toxins in 21 samples collected in 3 natural water reservoirs in the Ter River in Catalonia (NE of Spain) used to produce drinking water for Barcelona city (Spain).
Note: Reproducció del document publicat a:
It is part of: Toxins, 2020, vol. 12, num. 4, p. 247
Related resource:
ISSN: 2072-6651
Appears in Collections:Articles publicats en revistes (Enginyeria Química i Química Analítica)

Files in This Item:
File Description SizeFormat 
699083.pdf1.12 MBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons