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http://hdl.handle.net/2445/162922
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DC Field | Value | Language |
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dc.contributor.author | Amat Tusón, Mercedes | - |
dc.contributor.author | Bassas Sapé, Oriol | - |
dc.contributor.author | Llor Brunés, Núria | - |
dc.contributor.author | Cantó Espot, Margalida | - |
dc.contributor.author | Pérez Bosch, Maria | - |
dc.contributor.author | Molins i Grau, Elies | - |
dc.contributor.author | Bosch Cartes, Joan | - |
dc.date.accessioned | 2020-05-28T19:11:32Z | - |
dc.date.available | 2020-05-28T19:11:32Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0947-6539 | - |
dc.identifier.uri | http://hdl.handle.net/2445/162922 | - |
dc.description.abstract | A straightforward procedure for the synthesis of enantiopure polysubstituted piperidines is reported. It involves the direct generation of chiral non‐racemic oxazolo[3,2‐a ]piperidone lactams that already incorporate carbon substituents on the heterocyclic ring and the subsequent removal of the chiral auxiliary. The key step is a cyclocondensation reaction of (R )‐phenylglycinol or other amino alcohols with racemic or prochiral δ‐oxo (di)acid derivatives in highly stereoselective processes involving dynamic kinetic resolution and/or desymmetrization of diastereotopic or enantiotopic ester groups. | - |
dc.format.extent | 139 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Wiley-VCH | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1002/chem.200600420 | - |
dc.relation.ispartof | Chemistry-A European Journal, 2006, vol. 12, num. 30, p. 7872-7881 | - |
dc.relation.uri | https://doi.org/10.1002/chem.200600420 | - |
dc.rights | (c) Wiley-VCH, 2006 | - |
dc.source | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) | - |
dc.subject.classification | Síntesi orgànica | - |
dc.subject.classification | Alcaloides | - |
dc.subject.other | Organic synthesis | - |
dc.subject.other | Alkaloids | - |
dc.title | Dynamic Kinetic Resolution and Desymmetrization Processes: A Straightforward Methodology for the Enantioselective Synthesis of Piperidines | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 540137 | - |
dc.date.updated | 2020-05-28T19:11:32Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
Files in This Item:
File | Description | Size | Format | |
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540137.pdf | 1.42 MB | Adobe PDF | View/Open |
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