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Title: Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count
Author: Ruiz-de-Leon, Maria J.
Jimenez-Sousa, Maria A.
Moreno, Santiago
Garcia, Marcial
Gutierrez-Rivas, Monica
León García, Agathe
Montero-Alonso, Marta
Gonzalez-Garcia, Juan
Resino, Salvador
Rallón, Norma
Benito, José M.
Vallejo, Alejandro
ECRIS Network integrated in the Spanish AIDS Resea
Keywords: Cèl·lules T
VIH (Virus)
Micro RNAs
Marcadors bioquímics
T cells
HIV (Viruses)
Biochemical markers
Issue Date: 1-Aug-2019
Publisher: Elsevier
Abstract: Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137-0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = −0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found.
Note: Reproducció del document publicat a:
It is part of: Journal of Microbiology Immunology and Infection, 2019, vol. 52, num. 4, p. 667-671
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ISSN: 1684-1182
Appears in Collections:Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Medicina)

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