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https://hdl.handle.net/2445/163507| Title: | Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count |
| Author: | Ruiz-de-Leon, Maria J. Jimenez-Sousa, Maria A. Moreno, Santiago Garcia, Marcial Gutierrez-Rivas, Monica León García, Agathe Montero-Alonso, Marta Gonzalez-Garcia, Juan Resino, Salvador Rallón, Norma Benito, José M. Vallejo, Alejandro ECRIS Network integrated in the Spanish AIDS Resea |
| Keywords: | Cèl·lules T VIH (Virus) Micro RNAs Marcadors bioquímics T cells HIV (Viruses) MicroRNAs Biochemical markers |
| Issue Date: | 1-Aug-2019 |
| Publisher: | Elsevier |
| Abstract: | Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137-0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = −0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found. |
| Note: | Reproducció del document publicat a: https://doi.org/10.1016/j.jmii.2018.07.007 |
| It is part of: | Journal of Microbiology Immunology and Infection, 2019, vol. 52, num. 4, p. 667-671 |
| URI: | https://hdl.handle.net/2445/163507 |
| Related resource: | https://doi.org/10.1016/j.jmii.2018.07.007 |
| ISSN: | 1684-1182 |
| Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Medicina) |
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