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https://hdl.handle.net/2445/164192| Title: | Cyclocondensation reactions of 2-acyl-3-indoleacetic acid derivatives with phenylglycinol. Enantioselective synthesis of 1-substituted tetrahydro-b-carboline alkaloids |
| Author: | Amat Tusón, Mercedes Subrizi, Fabiana Elias, Viviane Llor Brunés, Núria Molins, Elies Bosch Cartes, Joan |
| Keywords: | Síntesi asimètrica Alcaloides Lactames Asymmetric synthesis Alkaloids Lactams |
| Issue Date: | Mar-2012 |
| Publisher: | Wiley-VCH |
| Abstract: | Cyclocondensation reactions between a variety of 2‐acyl‐3‐indoleacetic acid derivatives and (R )‐phenylglycinol were studied. Successful results were obtained from N ‐alkyl keto acid derivatives. The resulting tetracyclic lactams provide straightforward access to enantiopure 1‐substituted tetrahydro‐β‐carboline alkaloids. |
| Note: | Versió postprint del document publicat a: https://doi.org/10.1002/ejoc.201101718 |
| It is part of: | European Journal of Organic Chemistry, 2012, vol. 2012, num. 9, p. 1835-1842 |
| URI: | https://hdl.handle.net/2445/164192 |
| Related resource: | https://doi.org/10.1002/ejoc.201101718 |
| ISSN: | 1434-193X |
| Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) Articles publicats en revistes (Institut de Biomedicina (IBUB)) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 603301.pdf | 298.96 kB | Adobe PDF | View/Open |
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