Sequential ring-closing metathesis-vinyl halide Heck cyclization reactions: access to the tetracyclic ring system of ervitsine

Bennasar Fèlix, M. Lluïsa; Zulaica Gallego, Ester; Solé Arjó, Daniel; Alonso Serrano, Sandra

Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/164274

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DC Field	Value	Language
dc.contributor.author	Bennasar Fèlix, M. Lluïsa	-
dc.contributor.author	Zulaica Gallego, Ester	-
dc.contributor.author	Solé Arjó, Daniel	-
dc.contributor.author	Alonso Serrano, Sandra	-
dc.date.accessioned	2020-06-04T11:38:03Z	-
dc.date.available	2020-06-04T11:38:03Z	-
dc.date.issued	2012-06-17	-
dc.identifier.issn	0040-4020	-
dc.identifier.uri	http://hdl.handle.net/2445/164274	-
dc.description.abstract	A chemoselective indole-templated ring-closing metathesis is used to assemble the cyclohepta[b]indole substructure of the indole alkaloid ervitsine. A subsequent intramolecular Heck coupling of the resulting alkene functionality with an amino-tethered vinyl halide accomplishes the closure of the unique 2- azabicyclo[4.3.1]decane framework of the alkaloid with concomitant incorporation of the exocyclic Eethylidene substituent.	-
dc.format.extent	8 p.	-
dc.format.mimetype	application/pdf	-
dc.language.iso	eng	-
dc.publisher	Elsevier B.V.	-
dc.relation.isformatof	Versió postprint del document publicat a:	-
dc.relation.ispartof	Tetrahedron, 2012, vol. 68, num. 24, p. 4641-4648	-
dc.rights	(c) Elsevier B.V., 2012	-
dc.source	Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)	-
dc.subject.classification	Metàtesi (Química)	-
dc.subject.classification	Reaccions químiques	-
dc.subject.classification	Productes naturals	-
dc.subject.classification	Síntesi orgànica	-
dc.subject.classification	Alcaloides	-
dc.subject.other	Metathesis (Chemistry)	-
dc.subject.other	Chemical reactions	-
dc.subject.other	Natural products	-
dc.subject.other	Organic synthesis	-
dc.subject.other	Alkaloids	-
dc.title	Sequential ring-closing metathesis-vinyl halide Heck cyclization reactions: access to the tetracyclic ring system of ervitsine	-
dc.type	info:eu-repo/semantics/article	-
dc.type	info:eu-repo/semantics/acceptedVersion	-
dc.identifier.idgrec	622691	-
dc.date.updated	2020-06-04T11:38:03Z	-
dc.rights.accessRights	info:eu-repo/semantics/openAccess	-
Appears in Collections:	Articles publicats en revistes (Institut de Biomedicina (IBUB)) Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

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