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http://hdl.handle.net/2445/164347
Title: | Synthesis and Antiviral Evaluation of Bisnoradamantane Sulfites and Related Compounds |
Author: | Valverde Murillo, Elena Torres Costa, Eva Guardiola Bagán, Salvador Naesens, Lieve Vázquez Cruz, Santiago |
Keywords: | Sulfits Medicaments antivírics Síntesi de fàrmacs Sulfites Antiviral agents Drug synthesis |
Issue Date: | 2-Oct-2011 |
Publisher: | Bentham Science Publishers |
Abstract: | The reaction of a series of 1,2-diols with thionyl chloride led to bisnoradamantane sulfites in very good yields. The reaction has also been applied to related polycyclic scaffolds. The compounds have been tested for antiviral activity but none of them showed to be active. Several attempts to generate and trap SO from these polycyclic sulfites have been unsuccessful. |
Note: | Versió postprint del document publicat a: https://doi.org/10.2174/157340611794859299 |
It is part of: | Medicinal Chemistry, 2011, vol. 7, num. 2, p. 135-140 |
URI: | http://hdl.handle.net/2445/164347 |
Related resource: | https://doi.org/10.2174/157340611794859299 |
ISSN: | 1573-4064 |
Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) Articles publicats en revistes (Institut de Biomedicina (IBUB)) Divulgació i Premsa (Genètica, Microbiologia i Estadística) |
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