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Title: Alternative Methods to Animal Testing for the Safety Evaluation of Cosmetic Ingredients: An Overview
Author: Vinardell Martínez-Hidalgo, Ma. Pilar
Mitjans Arnal, Montserrat
Keywords: Indústria cosmètica
Experimentació animal
Avaluació del risc per la salut
Cosmetics industry
Animal experimentation
Health risk assessment
Issue Date: 31-Aug-2017
Publisher: MDPI
Abstract: The safety of cosmetics sold in Europe is based on the safety evaluation of each individual ingredient conducted by those responsible for putting the product on the market. However, those substances for which some concern exists with respect to human health (e.g., colorants, preservatives, UV-filters, nanomaterials) are evaluated at the European Commission level by a scientific committee, currently called the Scientific Committee on Consumer Safety (SCCS). According to the Cosmetics Regulation (European Commission, 2009), it is prohibited in the European Union (EU) to market cosmetic products and ingredients that have been tested on animals. However, the results of studies performed before the ban continue to be accepted. In the current study, we evaluated the use of in vitro methods in the dossiers submitted to the SCCS in the period between 2013 and 2016 based on the published reports issued by the scientific committee, which provides a scientific opinion on these dossiers. The results of this evaluation were compared with those of an evaluation conducted four years previously. We found that, despite a slight increase in the number of studies performed in vitro, the majority of studies submitted to the SCCS is still done principally in vivo and correspond to studies performed before the ban.
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It is part of: Cosmetics, 2017, vol. 4, num. 30
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ISSN: 2079-9284
Appears in Collections:Articles publicats en revistes (Bioquímica i Fisiologia)

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