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http://hdl.handle.net/2445/164558
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DC Field | Value | Language |
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dc.contributor.author | Romero, M. | - |
dc.contributor.author | Zanuy, M. | - |
dc.contributor.author | Rosell, E. | - |
dc.contributor.author | Cascante i Serratosa, Marta | - |
dc.contributor.author | Piulats, J. | - |
dc.contributor.author | Font Bardia, Ma. Mercedes | - |
dc.contributor.author | Balzirini, J. | - |
dc.contributor.author | de Clercq, E. | - |
dc.contributor.author | Pujol Dilmé, M. Dolors | - |
dc.date.accessioned | 2020-06-06T08:48:27Z | - |
dc.date.available | 2020-06-06T08:48:27Z | - |
dc.date.issued | 2015-01-27 | - |
dc.identifier.issn | 0223-5234 | - |
dc.identifier.uri | http://hdl.handle.net/2445/164558 | - |
dc.description.abstract | The aqueous extraction of the sesquiterpene lactone xanthatin from Xanthium spinosum L. favours the conversion of xanthinium to xanthatin via the loss of acetic acid. The cytotoxic (Hep-G2 and L1210 human cell lines) and antiviral activities of isolated xanthatin are established. This natural compound shows significant cytotoxicity against the Hep-G2 cell line and our experimental results reveal its strong anti-angiogenesis capacity in vitro. The structure of xanthatin is determined by spectroscopic methods and for the first time confirmed by X-ray diffraction. | - |
dc.format.extent | 26 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier Masson SAS | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1016/j.ejmech.2014.11.060 | - |
dc.relation.ispartof | European Journal of Medicinal Chemistry, 2015, vol. 90, p. 491-496 | - |
dc.relation.uri | https://doi.org/10.1016/j.ejmech.2014.11.060 | - |
dc.rights | (c) Elsevier Masson SAS, 2015 | - |
dc.source | Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada) | - |
dc.subject.classification | Plantes medicinals | - |
dc.subject.classification | Medicaments antivírics | - |
dc.subject.classification | Radiocristal·lografia | - |
dc.subject.other | Medicinal plants | - |
dc.subject.other | Antiviral agents | - |
dc.subject.other | X-ray crystallography | - |
dc.title | Optimization of Xanthatin Extraction from Xanthium spinosum L. and its cytotoxic, anti-angiogenesis and antiviral properties | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 648456 | - |
dc.date.updated | 2020-06-06T08:48:27Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 25481815 | - |
Appears in Collections: | Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada) |
Files in This Item:
File | Description | Size | Format | |
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648456.pdf | 952.34 kB | Adobe PDF | View/Open |
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