Please use this identifier to cite or link to this item:
Title: Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease
Author: Barreiro Capurro, Alicia
Mascaró Galy, José Manuel
Galindo, Beatriz Alejo
Giavedoni, Priscila
Carrera Álvarez, Cristina
Alós i Hernández, Llúcia
Puig i Sardà, Susana
Malvehy, J. (Josep)
Keywords: Melanoma
Cèl·lules mare
Càncer de pell
Stem cells
Skin cancer
Issue Date: 1-Sep-2019
Publisher: Society for the Publication of Acta Dermato-Venereologica
Abstract: Patients treated with haematopoietic stem cell transplantation are at increased risk of cutaneous malignant neoplasms. There are no reports on the characteristics of melanocytic lesions in patients with chronic graft versus host disease and the value of recognizing these difficult lesions in high-risk patients. The objective of this study is to describe the clinical and dermo scopic characteristics of melanocytic lesions in patients with chronic graft versus host disease in order to understand their morphology. A prospective cross-sectional study was performed; 10 melanocytic lesions on the trunk and extremities were selected from each patient. A statistically significant association was found between regression and high total dermoscopic score and 7-point checklist score. Lesions were excised or included in short-term digital follow-up. Melanocytic lesions in patients with chronic graft versus host disease developing after allogeneic-haematopoietic stem cell transplantation exhibit marked structural and colour changes similar to melanoma. This is believed to result from the inflammatory process associated with graft versus host disease.
Note: Reproducció del document publicat a:
It is part of: Acta Dermato-Venereologica, 2019, vol. 99, num. 9, p. 777-782
ISSN: 0001-5555
Appears in Collections:Articles publicats en revistes (Fonaments Clínics)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Files in This Item:
File Description SizeFormat 
692556.pdf683.2 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.