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http://hdl.handle.net/2445/164868
Title: | Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease |
Author: | Barreiro Capurro, Alicia Mascaró Galy, José Manuel Galindo, Beatriz Alejo Giavedoni, Priscila Carrera Álvarez, Cristina Alós i Hernández, Llúcia Puig i Sardà, Susana Malvehy, J. (Josep) |
Keywords: | Melanoma Dermatologia Cèl·lules mare Càncer de pell Melanoma Dermatology Stem cells Skin cancer |
Issue Date: | 1-Sep-2019 |
Publisher: | Society for the Publication of Acta Dermato-Venereologica |
Abstract: | Patients treated with haematopoietic stem cell transplantation are at increased risk of cutaneous malignant neoplasms. There are no reports on the characteristics of melanocytic lesions in patients with chronic graft versus host disease and the value of recognizing these difficult lesions in high-risk patients. The objective of this study is to describe the clinical and dermo scopic characteristics of melanocytic lesions in patients with chronic graft versus host disease in order to understand their morphology. A prospective cross-sectional study was performed; 10 melanocytic lesions on the trunk and extremities were selected from each patient. A statistically significant association was found between regression and high total dermoscopic score and 7-point checklist score. Lesions were excised or included in short-term digital follow-up. Melanocytic lesions in patients with chronic graft versus host disease developing after allogeneic-haematopoietic stem cell transplantation exhibit marked structural and colour changes similar to melanoma. This is believed to result from the inflammatory process associated with graft versus host disease. |
Note: | Reproducció del document publicat a: |
It is part of: | Acta Dermato-Venereologica, 2019, vol. 99, num. 9, p. 777-782 |
URI: | http://hdl.handle.net/2445/164868 |
ISSN: | 0001-5555 |
Appears in Collections: | Articles publicats en revistes (Fonaments Clínics) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) |
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