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http://hdl.handle.net/2445/164921
Title: | A Regenerative Endodontic Approach in Mature Ferret Teeth Using Rodent Preameloblast-conditioned Medium |
Author: | Bucchi Morales, María Cristina Gimeno Sandig, Álvaro Valdivia Gandur, Ivan Manzanares Céspedes, María Cristina Anta i Vinyals, Josep Maria de |
Keywords: | Endodòncia Polpa dental Dents Endodontics Dental pulp Teeth |
Issue Date: | 1-Jul-2019 |
Publisher: | International Institute of Anticancer Research |
Abstract: | Background: This study evaluated the effectiveness of a regenerative endodontic approach to regenerate the pulp tissue in mature teeth of ferret. The presence of odontoblast-like cells in the newly-formed tissue of teeth treated with or without preameloblast-conditioned medium was evaluated based on morphological criteria. Materials and methods: Twenty-four canines from six ferrets were treated. The pulp was removed, and the apical foramen was enlarged. After inducing the formation of a blood clot, a collagen sponge with or without preameloblast-conditioned medium was placed underneath the cementoenamel junction. The samples were analyzed at the eighth week of follow-up. Results: Vascularized connective tissue was observed in 50% of teeth, without differences between groups. The tissue occupied the apical third of the root canals. Odontoblast-like cells were not observed in any group. Conclusion: Revitalization of mature teeth is possible, at least in the apical third of the root canal. Further experimental research is needed to produce more reliable outcomes. |
Note: | Reproducció del document publicat a: https://doi.org/10.21873/invivo.11584 |
It is part of: | In Vivo, 2019, vol. 33, num. 4, p. 1143-1150 |
URI: | http://hdl.handle.net/2445/164921 |
Related resource: | https://doi.org/10.21873/invivo.11584 |
ISSN: | 0258-851X |
Appears in Collections: | Articles publicats en revistes (Patologia i Terapèutica Experimental) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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