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http://hdl.handle.net/2445/166523
Title: | Risk factors for surgical site infection after craniotomy: a prospective cohort study |
Author: | Jiménez Martínez, Emilio Cuervo Requena, Guillermo Hornero, Ana Ciercoles, Pilar Gabarrós, Andreu Cabellos Mínguez, Ma. Carmen Pelegrin, Ivan Garcia-Somoza, Dolores Adamuz Tomás, Jordi Carratalà, Jordi Pujol, Miguel |
Keywords: | Operacions quirúrgiques Infeccions Craniometria Surgical operations Infections Craniometry |
Issue Date: | 2-May-2019 |
Publisher: | BioMed Central |
Abstract: | Background: Although surgical site infection after craniotomy (SSI-CRAN) is a serious complication, risk factors for its development have not been well defined. We aim to identify the risk factors for developing SSI-CRAN in a large prospective cohort of adult patients undergoing craniotomy. Methods: A series of consecutive patients who underwent craniotomy at a university hospital from January 2013 to December 2015 were prospectively assessed. Demographic, epidemiological, surgical, clinical and microbiological data were collected. Patients were followed up in an active post-discharge surveillance programm e for up to one year after surgery. Multivariate analysis was carried out to identify independent risk factors for SSI-CRAN. Results: Among the 595 patients who underwent craniotomy, 91 (15.3%) episodes of SSI-CRAN were recorded, 67 (73.6%) of which were organ/space. Baseline demographic characteristics were similar among patients who developed SSI-CRAN and those who did not. The most frequent causative Gram-positive organisms were Cutibacterium acnes (23.1%) and Staphylococcus epidermidis (23.1%), whereas Enterobacter cloacae (12.1%) was the most commonly isolated Gram-negative agent. In the univariate analysis the factors associated with SSI-CRAN were ASA score > 2 (48.4% vs. 35.5% in SSI-CRAN and no SSI-CRAN respectively, p = 0.025), extrinsic tumour (28.6% vs. 19.2%, p = 0.05), and re-intervention (4.4% vs. 1.4%, p = < 0.001). In the multivariate analysis, ASA score > 2 (AOR: 2.26, 95% CI: 1.32-3.87; p = .003) and re-intervention (OR: 8.93, 95% CI: 5.33-14.96; p < 0.001) were the only factors independently associated with SSI-CRAN. Conclusion: The risk factors and causative agents of SSI-CRAN identified in this study should be considered in the design of preventive strategies aimed to reduce the incidence of this serious complication. |
Note: | Reproducció del document publicat a: https://doi.org/10.1186/s13756-019-0525-3 |
It is part of: | Antimicrobial Resistance and Infection Control, 2019, vol. 8, p. 69 |
URI: | http://hdl.handle.net/2445/166523 |
Related resource: | https://doi.org/10.1186/s13756-019-0525-3 |
ISSN: | 2047-2994 |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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