Please use this identifier to cite or link to this item:
https://hdl.handle.net/2445/168977
Title: | STATegra, a comprehensive multi-omics dataset of B-cell differentiation in mouse |
Author: | Gomez Cabrero, David Tarazona, Sonia Ferreirós Vidal, Isabel Ramirez, Ricardo N. Company, Carlos Schmidt, Andreas Reijmers, Theo von Saint Paul, Veronica Marabita, Francesco Rodríguez Ubreva, Javier García Gómez, Antonio Carroll, Tom Cooper, Lee Liang, Ziwei Dharmalingam, Gopuraja van der Kloet, Frans Harms, Amy C. Balzano Nogueira, Leandro Lagani, Vincenzo Tsamardinos, Ioannis Lappe, Michael Maier, Dieter Westerhuis, Johan A. Hankemeier, Thomas Imhof, Axel Ballestar Tarín, Esteban Mortazavi, Ali Merkenschlager, Matthias Egner, Jesper Conesa, Ana |
Keywords: | Fisiologia cel·lular Cèl·lules B Ratolins (Animals de laboratori) Cell physiology B cells Mice (Laboratory animals) |
Issue Date: | 31-Oct-2019 |
Publisher: | Nature Publishing Group |
Abstract: | Multi-omics approaches use a diversity of high-throughput technologies to profile the different molecular layers of living cells. Ideally, the integration of this information should result in comprehensive systems models of cellular physiology and regulation. However, most multi-omics projects still include a limited number of molecular assays and there have been very few multi-omic studies that evaluate dynamic processes such as cellular growth, development and adaptation. Hence, we lack formal analysis methods and comprehensive multi-omics datasets that can be leveraged to develop true multi-layered models for dynamic cellular systems. Here we present the STAT egra multi-omics dataset that combines measurements from up to 10 different omics technologies applied to the same biological system, namely the well-studied mouse pre-B-cell differentiation. STATegra includes |
Note: | Reproducció del document publicat a: https://doi.org/10.1038/s41597-019-0202-7 |
It is part of: | Scientific Data, 2019, vol. 6, p. 256 |
URI: | https://hdl.handle.net/2445/168977 |
Related resource: | https://doi.org/10.1038/s41597-019-0202-7 |
Appears in Collections: | Publicacions de projectes de recerca finançats per la UE Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Gomez-CabreroD.pdf | 3.02 MB | Adobe PDF | View/Open |
This item is licensed under a
Creative Commons License