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Title: Potential pathogenicity of Aeromonas hydrophila complex strains isolated from clinical, food, and environmental sources
Author: Albarral Ávila, Vicenta
Sanglas Baulenas, Ariadna
Palau de Miguel, Montserrat
Miñana i Galbis, David
Fusté Munné, M. Carme
Keywords: Bacteris gramnegatius
Malalties infeccioses
Gram-negative bacteria
Communicable diseases
Issue Date: 2016
Publisher: NRC Research Press
Abstract: <i>Aeromonas</i> are autochthonous inhabitants of aquatic environments, including chlorinated and polluted waters, although they can also be isolated from a wide variety of environmental and clinical sources. They cause infections in vertebrates and invertebrates and are considered to be an emerging pathogen in humans, producing intestinal and extra-intestinal diseases. Most of the clinical isolates correspond to <i>A. hydrophila</i>, <i>A. caviae</i>, and <i>A. veronii</i> bv. Sobria, which are described as the causative agents of wound infections, septicaemia, and meningitis in immunocompromised people, and diarrhoea and dysenteric infections in the elderly and children. The pathogenic factors associated with <i>Aeromonas</i> are multifactorial and involve structural components, siderophores, quorum-sensing mechanisms, secretion systems, extracellular enzymes, and exotoxins. In this study, we analysed a representative number of clinical and environmental strains belonging to the <i>A. hydrophila</i> species complex to evaluate their potential pathogenicity. We thereby detected their enzymatic activities and antibiotic susceptibility pattern and the presence of virulence genes (<i>aer</i>, <i>alt</i>, <i>ast</i>, and <i>ascV</i>). The notably high prevalence of these virulence factors, even in environmental strains, indicated a potential pathogenic capacity. Additionally, we determined the adhesion capacity and cytopathic effects of this group of strains in Caco-2 cells. Most of the strains exhibited adherence and caused complete lysis.
Note: Versió postprint del document publicat a:
It is part of: Canadian Journal of Microbiology, 2016, vol. 62, num. 4, p. 296-306
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ISSN: 0008-4166
Appears in Collections:Articles publicats en revistes (Biologia, Sanitat i Medi Ambient)

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