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http://hdl.handle.net/2445/171510
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DC Field | Value | Language |
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dc.contributor.author | Ruiz Bustillo, Sonia | - |
dc.contributor.author | Ivern, Consol | - |
dc.contributor.author | Badosa-Marcé, Neus | - |
dc.contributor.author | Farré, Nuria | - |
dc.contributor.author | Marco, Esther | - |
dc.contributor.author | Bruguera, Jordi | - |
dc.contributor.author | Cladellas Capdevila, Mercè | - |
dc.contributor.author | Enjuanes, Cristina | - |
dc.contributor.author | Cainzos Achirica, Miguel | - |
dc.contributor.author | Marti Almor, Julio | - |
dc.contributor.author | Comín Colet, Josep | - |
dc.date.accessioned | 2020-10-26T10:37:02Z | - |
dc.date.available | 2020-10-26T10:37:02Z | - |
dc.date.issued | 2019-06-01 | - |
dc.identifier.uri | http://hdl.handle.net/2445/171510 | - |
dc.description.abstract | Background and aims: Lack of achievement of secondary prevention objectives in patients with ischaemic heart disease remains an unmet need in this patient population. We aimed at evaluating the six-month efficacy of an intensive lipid-lowering intervention, coordinated by nurses and implemented after hospital discharge, in patients hospitalized for an ischaemic heart disease event. Methods: Randomized controlled trial, in which a nurse-led intervention including periodic follow-up, serial lipid level controls, and subsequent optimization of lipid-lowering therapy, if appropriate, was compared with standard of care alone in terms of serum lipid-level control at six months after discharge. Results: The nurse-led intervention was associated with an improved management of low-density lipoprotein (LDL) cholesterol levels compared with standard of care alone: LDL cholesterol levels <= 100 mg/dL were achieved in 97% participants in the intervention arm as compared with 67% in the usual care arm (p value <0.001), the LDL cholesterol <= 70 mg/dL target recommended by the 2016 European Society of Cardiology guidelines was achieved in 62% vs. 37% participants (p value 0.047) and the LDL cholesterol reduction of > 50% recommended by the American College of Cardiology/American Heart Association in 2013 was achieved in 25.6% of participants in the intervention arm as compared with 2.6% in the usual care arm (p value 0.007). The intervention was also associated with improved blood pressure control among individuals with hypertension. Conclusions: Our findings highlight the opportunity that nurse-led, intensive, post-discharge follow-up plans may represent for achieving LDL cholesterol guideline-recommended management objectives in patients with ischaemic heart disease. These findings should be replicated in larger cohorts. | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Sage Publications Ltd. | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1177/1474515119831511 | - |
dc.relation.ispartof | European Journal of Cardiovascular Nursing, 2019, vol. 18, num. 5, p. 366-374 | - |
dc.relation.uri | https://doi.org/10.1177/1474515119831511 | - |
dc.rights | cc by-nc-nd (c) Ruiz Bustillo et al., 2019 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Isquèmia | - |
dc.subject.classification | Malalties del cor | - |
dc.subject.other | Ischemia | - |
dc.subject.other | Heart diseases | - |
dc.title | Efficacy of a nurse-led lipid-lowering secondary prevention intervention in patients hospitalized for ischemic heart disease: A pilot randomized controlled trial | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.date.updated | 2020-10-26T09:20:08Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 30757908 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) Articles publicats en revistes (Ciències Clíniques) |
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File | Description | Size | Format | |
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Ruiz-BustilloS.pdf | 457.8 kB | Adobe PDF | View/Open |
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