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http://hdl.handle.net/2445/171648
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DC Field | Value | Language |
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dc.contributor.author | Garcia Vidal, Carolina | - |
dc.contributor.author | Sanjuan, Gemma | - |
dc.contributor.author | Moreno García, Estela | - |
dc.contributor.author | Puerta-Alcalde, Pedro | - |
dc.contributor.author | Garcia-Pouton, Nicole | - |
dc.contributor.author | Chumbita, Mariana | - |
dc.contributor.author | Fernández Pittol, Mariana José | - |
dc.contributor.author | Pitart, Cristina | - |
dc.contributor.author | Inciarte Portillo, Alexy | - |
dc.contributor.author | Bodro, Marta | - |
dc.contributor.author | Morata, Laura | - |
dc.contributor.author | Ambrosioni, Juan | - |
dc.contributor.author | Grafia, Ignacio | - |
dc.contributor.author | Meira, Fernanda | - |
dc.contributor.author | Macaya, Irene | - |
dc.contributor.author | Cardozo Espinola, Celia | - |
dc.contributor.author | Casals Pascual, Climent | - |
dc.contributor.author | Tellez, Adrian | - |
dc.contributor.author | Castro Rebollo, Pedro | - |
dc.contributor.author | Marco Reverté, Francesc | - |
dc.contributor.author | García Alcaide, Felipe | - |
dc.contributor.author | Mensa Pueyo, Josep | - |
dc.contributor.author | Martínez, José Antonio (Martínez Martínez) | - |
dc.contributor.author | Soriano Viladomiu, Alex | - |
dc.contributor.author | COVID-19 Researchers Group | - |
dc.date.accessioned | 2020-10-30T18:06:10Z | - |
dc.date.available | 2021-07-30T05:10:18Z | - |
dc.date.issued | 2020-07-31 | - |
dc.identifier.issn | 1198-743X | - |
dc.identifier.uri | http://hdl.handle.net/2445/171648 | - |
dc.description.abstract | Objectives: To describe the burden, epidemiology and outcomes of co-infections and superinfections occurring in hospitalized patients with coronavirus disease 2019 (COVID-19). Methods: We performed an observational cohort study of all consecutive patients admitted for ≥48 hours to the Hospital Clinic of Barcelona for COVID-19 (28 February to 22 April 2020) who were discharged or dead. We describe demographic, epidemiologic, laboratory and microbiologic results, as well as outcome data retrieved from electronic health records. Results: Of a total of 989 consecutive patients with COVID-19, 72 (7.2%) had 88 other microbiologically confirmed infections: 74 were bacterial, seven fungal and seven viral. Community-acquired co-infection at COVID-19 diagnosis was uncommon (31/989, 3.1%) and mainly caused by Streptococcus pneumoniae and Staphylococcus aureus. A total of 51 hospital-acquired bacterial superinfections, mostly caused by Pseudomonas aeruginosa and Escherichia coli, were diagnosed in 43 patients (4.7%), with a mean (SD) time from hospital admission to superinfection diagnosis of 10.6 (6.6) days. Overall mortality was 9.8% (97/989). Patients with community-acquired co-infections and hospital-acquired superinfections had worse outcomes. Conclusions: Co-infection at COVID-19 diagnosis is uncommon. Few patients developed superinfections during hospitalization. These findings are different compared to those of other viral pandemics. As it relates to hospitalized patients with COVID-19, such findings could prove essential in defining the role of empiric antimicrobial therapy or stewardship strategies. | - |
dc.format.extent | 25 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | European Society of Clinical Microbiology and Infectious Diseases | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1016/j.cmi.2020.07.041 | - |
dc.relation.ispartof | Clinical Microbiology and Infection, 2020, vol. S1198-743X | - |
dc.relation.uri | https://doi.org/10.1016/j.cmi.2020.07.041 | - |
dc.rights | (c) Garcia Vidal, Carolina et al., 2020 | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | COVID-19 | - |
dc.subject.classification | Infeccions | - |
dc.subject.other | COVID-19 | - |
dc.subject.other | Infections | - |
dc.title | Incidence of co-infections and superinfections in hospitalised patients with COVID-19: a retrospective cohort study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 704106 | - |
dc.date.updated | 2020-10-30T18:06:11Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 32745596 | - |
Appears in Collections: | Articles publicats en revistes (ISGlobal) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Medicina) |
Files in This Item:
File | Description | Size | Format | |
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704106.pdf | 481.85 kB | Adobe PDF | View/Open |
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