Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/171741
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kliemann, Nathalie | - |
dc.contributor.author | Murphy, Neil | - |
dc.contributor.author | Viallon, Vivian | - |
dc.contributor.author | Freisling, Heinz | - |
dc.contributor.author | Tsilidis, Konstantinos K. | - |
dc.contributor.author | Rinaldi, Sabina | - |
dc.contributor.author | Mancini, Francesca Romana | - |
dc.contributor.author | Fagherazzi, Guy | - |
dc.contributor.author | Boutron-Ruault, Marie-Christine | - |
dc.contributor.author | Boeing, Heiner | - |
dc.contributor.author | Schulze, Matthias B. | - |
dc.contributor.author | Masala, Giovanna | - |
dc.contributor.author | Krogh, Vittorio | - |
dc.contributor.author | Sacerdote, Carlotta | - |
dc.contributor.author | Santucci de Magistris, Maria | - |
dc.contributor.author | Bueno de Mesquita, H. Bas | - |
dc.contributor.author | Weiderpass, Elisabete | - |
dc.contributor.author | Kühn, Tilman | - |
dc.contributor.author | Kaaks, Rudolf | - |
dc.contributor.author | Jakszyn, Paulka | - |
dc.contributor.author | Redondo Sánchez, Daniel | - |
dc.contributor.author | Amiano, Pilar | - |
dc.contributor.author | Chirlaque, María Dolores | - |
dc.contributor.author | Barricarte, Aurelio | - |
dc.contributor.author | Ericson, Ulrika | - |
dc.contributor.author | Drake, Isabel | - |
dc.contributor.author | Nøst, Therese Haugdahl | - |
dc.contributor.author | Aune, Dagfinn | - |
dc.contributor.author | May, Anne M. | - |
dc.contributor.author | Tjønneland, Anne | - |
dc.contributor.author | Dahm, Christina C. | - |
dc.contributor.author | Overvad, Kim | - |
dc.contributor.author | Tumino, Rosario | - |
dc.contributor.author | Quirós, J. Ramón | - |
dc.contributor.author | Trichopoulou, Antonia | - |
dc.contributor.author | Karakatsani, Anna | - |
dc.contributor.author | Vecchia, Carlo La | - |
dc.contributor.author | Nilsson, Lena Maria | - |
dc.contributor.author | Riboli, Elio | - |
dc.contributor.author | Huybrechts, Inge | - |
dc.contributor.author | Gunter, Marc J. | - |
dc.date.accessioned | 2020-11-04T10:59:30Z | - |
dc.date.available | 2020-11-04T10:59:30Z | - |
dc.date.issued | 2020-08-01 | - |
dc.identifier.uri | http://hdl.handle.net/2445/171741 | - |
dc.description.abstract | Emerging evidence suggests that a metabolic profile associated with obesity may be a more relevant risk factor for some cancers than adiposity per se. Basal metabolic rate (BMR) is an indicator of overall body metabolism and may be a proxy for the impact of a specific metabolic profile on cancer risk. Therefore, we investigated the association of predicted BMR with incidence of 13 obesity-related cancers in the European Prospective Investigation into Cancer and Nutrition (EPIC). BMR at baseline was calculated using the WHO/FAO/UNU equations and the relationships between BMR and cancer risk were investigated using multivariable Cox proportional hazards regression models. A total of 141,295 men and 317,613 women, with a mean follow-up of 14 years were included in the analysis. Overall, higher BMR was associated with a greater risk for most cancers that have been linked with obesity. However, among normal weight participants, higher BMR was associated with elevated risks of esophageal adenocarcinoma (hazard ratio per 1-standard deviation change in BMR [HR1-SD]: 2.46; 95% CI 1.20; 5.03) and distal colon cancer (HR1-SD: 1.33; 95% CI 1.001; 1.77) among men and with proximal colon (HR1-SD: 1.16; 95% CI 1.01; 1.35), pancreatic (HR1-SD: 1.37; 95% CI 1.13; 1.66), thyroid (HR1-SD: 1.65; 95% CI 1.33; 2.05), postmenopausal breast (HR1-SD: 1.17; 95% CI 1.11; 1.22) and endometrial (HR1-SD: 1.20; 95% CI 1.03; 1.40) cancers in women. These results indicate that higher BMR may be an indicator of a metabolic phenotype associated with risk of certain cancer types, and may be a useful predictor of cancer risk independent of body fatness. | - |
dc.format.extent | 14 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | ca |
dc.publisher | Wiley | ca |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1002/ijc.32753 | - |
dc.relation.ispartof | International Journal of Cancer, 2020, vol. 147, num. 3, p. 648-661 | - |
dc.relation.uri | https://doi.org/10.1002/ijc.32753 | - |
dc.rights | (c) International Agency for Research on Cancer (IARC/WHO), 2020 | - |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Càncer | - |
dc.subject.classification | Nutrició | - |
dc.subject.other | Cancer | - |
dc.subject.other | Nutrition | - |
dc.title | Predicted basal metabolic rate and cancer risk in the European Prospective Investigation into Cancer and Nutrition | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.date.updated | 2020-11-03T17:08:39Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 31652358 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
KliemannN.pdf | 988.37 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.