Miniatura

Fitxers

697960.pdf (533.66 KB)

Tipus de document

Article

Versió

Versió acceptada

Data de publicació

2018

Tots els drets reservats

Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/172819

Prevalence of sleep disorders in adults with down syndrome: a comparative study of subjective, actigraphic and polygraphic findings

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.5664/jcsm.7382

Resum

STUDY OBJECTIVES:Sleep problems are often undetected in adults with Down syndrome (DS). Our objective was to determine the prevalence of sleep disorders in adults with DS through self-reported and objective sleep measures. METHODS:We performed a community-based cross-sectional study of 54 adults with DS not referred for sleep disorders. Two polysomnography (PSG) sleep studies were performed. Sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI); daytime sleepiness was evaluated using the Epworth Sleepiness Scale (ESS) and the risk for the sleep apnea syndrome (OSA) was identified using the Berlin Questionnaire (BQ). Participants' sleep/wake pattern was assessed from sleep diaries and by wrist actigraphy. PSQI, ESS, and PSG measures were compared with 35 sex-, age-, and body mass index-matched patients in the control groups. RESULTS:In PSG measures, adults with DS showed lower sleep efficiency (69 ± 17.7 versus 81.6 ± 11; P < .001), less rapid eye movement sleep (9.4 ± 5.8 versus 19.4 ± 5.1; P < .001), a higher prevalence of OSA (78% versus 14%; P < .001), and a higher apnea-hypopnea index (23.5 ± 24.5 versus 3.8 ± 10.5; P < .001) than patients in the control group. In the DS group, the questionnaires (mean PSQI 3.7 ± 2.9; mean ESS 6.3 ± 4.5 and mean BQ 1 ± 0) did not reflect the sleep disturbances detected on the PSG. Actigraphy data recorded daytime sleep that was not self-reported (118.2 ± 104.2 minutes). CONCLUSIONS:Adults with DS show severe sleep disruption and a high prevalence of OSA, undetected by self-reported sleep measures. Actigraphy, PSG, and validated simplified devices for screening OSA should be routinely recommended for this population because treatment of sleep disorders can contribute to healthy aging.

Matèries

Síndrome de Down, Trastorns del son

Matèries (anglès)

Down syndrome, Sleep disorders

Citació

Col·leccions

Articles publicats en revistes (Patologia i Terapèutica Experimental)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

GIMÉNEZ, Sandra, VIDELA, Laura, ROMERO, Sergio, BENEJAM, Bessy, CLOS, Susana, FERNÁNDEZ, Susana, MARTÍNEZ, Maribel, CARMONA-IRAGUI, Maria, ANTONIJOAN ARBÓS, Rosa ma. (rosa maría), MAYOS, Mercedes, FORTUNA, Ana, PEÑACOBA, Patricia, PLAZA, Vicente, OSORIO, Ricardo s., SHARMA, Ram a., BARDÉS, Ignasi, REBILLAT, Anne  sophie, LLEÓ BISA, Alberto, BLESA GONZÁLEZ, Rafael, VIDELA, Sebastià, FORTEA ORMAECHEA, Juan. Prevalence of sleep disorders in adults with down syndrome: a comparative study of subjective, actigraphic and polygraphic findings. _Journal of Clinical Sleep Medicine_. 2018. Vol. 14, núm. 10, pàgs. 1725-1733. [consulta: 23 de gener de 2026]. ISSN: 1550-9389. [Disponible a: https://hdl.handle.net/2445/172819]

Exportar metadades

JSON - METS

Compartir registre