Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/173252
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Abelenda Alonso, Gabriela | - |
dc.contributor.author | Rombauts, Alexander | - |
dc.contributor.author | Gudiol González, Carlota | - |
dc.contributor.author | Meije, Yolanda | - |
dc.contributor.author | Ortega, Lucia | - |
dc.contributor.author | Clemente, Mercedes | - |
dc.contributor.author | Ardanuy Tisaire, María Carmen | - |
dc.contributor.author | Niubó, Jordi | - |
dc.contributor.author | Carratalà, Jordi | - |
dc.date.accessioned | 2021-01-20T16:38:51Z | - |
dc.date.available | 2021-01-20T16:38:51Z | - |
dc.date.issued | 2020-03-01 | - |
dc.identifier.uri | http://hdl.handle.net/2445/173252 | - |
dc.description.abstract | Background. Relevance of viral and bacterial coinfection (VBC) in non-intensive care unit (ICU) hospitalized adults with community-acquired pneumonia (CAP) is poorly characterized. We aim to determine risk factors, features, and outcomes of VBCCAP in this setting. Methods. This is a prospective cohort of adults admitted to conventional wards with CAP. Patients were divided into VBC-CAP, viral CAP (V-CAP), and bacterial CAP (B-CAP) groups. Independent risk and prognostic factors for VBC-CAP were identified. Results. We documented 1123 episodes: 57 (5.1%) VBC-CAP, 98 (8.7%) V-CAP, and 968 (86.1%) B-CAP. Patients with VBCCAP were younger than those with B-CAP (54 vs 71 years; P < .001). Chronic respiratory disease was more frequent in patients with VBC-CAP than in those with V-CAP (26.3% vs 14.3%%; P = .001). Among those with influenza (n = 153), the VBC-CAP group received empirical oseltamivir less often (56.1% vs 73.5%; P < .001). Patients with VBC-CAP also had more respiratory distress (21.1% VBC-CAP; 19.4% V-CAP, and 9.8% B-CAP; P < .001) and required ICU admission more often (31.6% VBC-CAP, 31.6% V-CAP, and 12.8% B-CAP; P < .001). Me 30-day case-fatality rate was 3.5% in the VBC-CAP group, 3.1% in the V-CAP group, and 6.3% in the B-CAP group (P = .232). Furthermore, VBC-CAP was associated with severity criteria (odds ratio [OR], 5.219; P < .001) and lack of empirical oseltamivir therapy in influenza cases (OR, 0.401; P < .043). Conclusions. Viral and bacterial coinfection-CAP involved younger patients with comorbidities and with poor influenza vaccination rate. Patients with VBC-CAP presented more respiratory complications and more often required ICU admission. Nevertheless, 30-day mortality rate was low and related either to severity criteria or to delayed initiation of oseltamivir therapy. | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Oxford University Press Inc. | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1093/ofid/ofaa066 | - |
dc.relation.ispartof | Open Forum Infectious Diseases, 2020, vol. 7, num. 3 | - |
dc.relation.uri | https://doi.org/10.1093/ofid/ofaa066 | - |
dc.rights | cc by-nc-nd (c) Abelenda Alonso et al., 2020 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | - |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Pneumònia adquirida a la comunitat | - |
dc.subject.classification | Influenzavirus | - |
dc.subject.other | Community-acquired pneumonia | - |
dc.subject.other | Influenza viruses | - |
dc.title | Influenza and Bacterial Coinfection in Adults With Community-Acquired Pneumonia Admitted to Conventional Wards: Risk Factors, Clinical Features, and Outcomes | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2020-12-21T13:14:13Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 32206675 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
ofaa066.pdf | 200.79 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License