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Title: Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into cancer and Nutrition
Author: Obón Santacana, Mireia
Luján Barroso, Leila
Freisling, Heinz
Naudin, Sabine
Boutron-Ruault, Marie-Christine
Mancini, Francesca Romana
Rebours, Vinciane
Kühn, Tilman
Katzke, Verena
Boeing, Heiner
Tjønneland, Anne
Olsen, Anja
Overvad, Kim
Lasheras, Cristina
Rodríguez Barranco, Miguel
Amiano, Pilar
Santiuste, Carmen
Ardanaz, Eva
Khaw, Kay-Thee
Wareham, Nicholas J.
Schmidt, Julie A.
Aune, Dagfinn
Trichopoulou, Antonia
Thriskos, Paschalis
Peppa, Eleni
Masala, Giovanna
Grioni, Sara
Tumino, Rosario
Panico, Salvatore
Bueno de Mesquita, H. Bas
Sciannameo, Veronica
Vermeulen, Roel
Sonestedt, Emily
Sund, Mali
Weiderpass, Elisabete
Skeie, Guri
González, Carlos A.
Riboli, Elio
Duell, Eric J.
Keywords: Càncer
Cuina (Nous)
Cooking (Nuts)
Issue Date: May-2019
Publisher: Wiley
Abstract: Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estimate hazards ratio (HR) and 95% confidence intervals (95% CI) for nut intake and PDAC risk. Information on intake of nuts was obtained from the EPIC country‐specific dietary questionnaires. After a mean follow‐up of 14 years, 476,160 participants were eligible for the present study and included 1,283 PDAC cases. No association was observed between consumption of nuts and PDAC risk (highest intake vs nonconsumers: HR, 0.89; 95% CI, 0.72-1.10; p‐trend = 0.70). Furthermore, no evidence for effect‐measure modification was observed when different subgroups were analyzed. Overall, in EPIC, the highest intake of nuts was not statistically significantly associated with PDAC risk.
Note: Versió postprint del document publicat a:
It is part of: International Journal of Cancer, 2019, vol. 146, num. 15, p. 76-84
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ISSN: 0020-7136
Appears in Collections:Articles publicats en revistes (Infermeria de Salut Pública, Salut mental i Maternoinfantil)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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