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http://hdl.handle.net/2445/173757
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DC Field | Value | Language |
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dc.contributor.author | Cai, Lina | - |
dc.contributor.author | Wheeler, Eleanor | - |
dc.contributor.author | Kerrison, Nicola D. | - |
dc.contributor.author | Luan, Jian’an | - |
dc.contributor.author | Deloukas, Panos | - |
dc.contributor.author | Franks, Paul W. | - |
dc.contributor.author | Amiano, Pilar | - |
dc.contributor.author | Ardanaz, Eva | - |
dc.contributor.author | Bonet Bonet, Catalina | - |
dc.contributor.author | Fagherazzi, Guy | - |
dc.contributor.author | Groop, Leif C. | - |
dc.contributor.author | Kaaks, Rudolf | - |
dc.contributor.author | Huerta Castaño, José María | - |
dc.contributor.author | Masala, Giovanna | - |
dc.contributor.author | Nilsson, Peter M. | - |
dc.contributor.author | Overvad, Kim | - |
dc.contributor.author | Pala, Valeria | - |
dc.contributor.author | Panico, Salvatore | - |
dc.contributor.author | Rodriguez Barranco, M | - |
dc.contributor.author | Rolandsson, Olov | - |
dc.contributor.author | Sacerdote, Carlotta | - |
dc.contributor.author | Schulze, Matthias B. | - |
dc.contributor.author | Spijkerman, Annemieke M. W. | - |
dc.contributor.author | Tjønneland, Anne | - |
dc.contributor.author | Tumino, Rosario | - |
dc.contributor.author | van der Schouw, Yvonne T. | - |
dc.contributor.author | Sharp, Stephen J. | - |
dc.contributor.author | Forouhi, Nita G. | - |
dc.contributor.author | Riboli, Elio | - |
dc.contributor.author | McCarthy, Mark I. | - |
dc.contributor.author | Barroso, Inês | - |
dc.contributor.author | Langenberg, Claudia | - |
dc.contributor.author | Wareham, Nicholas J. | - |
dc.date.accessioned | 2021-02-09T09:27:22Z | - |
dc.date.available | 2021-02-09T09:27:22Z | - |
dc.date.issued | 2020-11-13 | - |
dc.identifier.uri | http://hdl.handle.net/2445/173757 | - |
dc.description.abstract | Type 2 diabetes (T2D) is a global public health challenge. Whilst the advent of genome-wide association studies has identified >400 genetic variants associated with T2D, our understanding of its biological mechanisms and translational insights is still limited. The EPIC-InterAct project, centred in 8 countries in the European Prospective Investigations into Cancer and Nutrition study, is one of the largest prospective studies of T2D. Established as a nested case-cohort study to investigate the interplay between genetic and lifestyle behavioural factors on the risk of T2D, a total of 12,403 individuals were identified as incident T2D cases, and a representative sub-cohort of 16,154 individuals was selected from a larger cohort of 340,234 participants with a follow-up time of 3.99 million person-years. We describe the results from a genome-wide association analysis between more than 8.9 million SNPs and T2D risk among 22,326 individuals (9,978 cases and 12,348 non-cases) from the EPIC-InterAct study. The summary statistics to be shared provide a valuable resource to facilitate further investigations into the genetics of T2D. | - |
dc.format.extent | 6 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Nature Research | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1038/s41597-020-00716-7 | - |
dc.relation.ispartof | Scientific Data, 2020, vol. 7 | - |
dc.relation.uri | https://doi.org/10.1038/s41597-020-00716-7 | - |
dc.rights | cc by (c) Cai et al., 2020 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | - |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Diabetis | - |
dc.subject.classification | Malalties cardiovasculars | - |
dc.subject.classification | Mortalitat | - |
dc.subject.other | Diabetes | - |
dc.subject.other | Cardiovascular diseases | - |
dc.subject.other | Mortality | - |
dc.title | Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2021-02-08T10:16:02Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 33188205 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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