Title: | Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years |
Author: | Frangou, Sophia Modabbernia, Amirhossein Williams, Steven C. R. Papachristou, Efstathios Doucet, Gaelle E. Agartz, Ingrid Aghajani, Moji Akudjedu, Theophilus N. Albajes Eizagirre, Anton Alnæs, Dag Alpert, Kathryn I. Zanetti, Marcus V. Naaijen, Jilly Najt, Pablo Trollor, Julian N. Nakao, Tomohiro Völzke, Henry Buitelaar, Jan K. West, John D. Fouche, Jean Paul Hibar, Derrek P. Mazoyer, Bernard Serpa, Mauricio H. Nordvik, Jan E. Crespo Facorro, Benedicto Pomarol-Clotet, Edith Ziegler, Georg C. Portella, Maria J. Potkin, Steven G. Radua, Joaquim Davey, Christopher Asherson, Philip Chubar, Victoria Klyushnik, Tatyana P. Whalley, Heather Reif, Andreas Oosterlaan, Jaap Uhlmann, Anne Sacchet, Matthew D. Fisher, Simon E. Schmaal, Lianne Buckner, Randy L. Schnell, Knut Clark, Vincent P. Schumann, Gunter Sim, Kang Fuentes Claramonte, Paola Smoller, Jordan W. Ehrlich, Stefan Canales Rodríguez, Erick Jorge Bertolino, Alessandro Sommer, Iris Sánchez Juan, Pascual Westlye, Lars T. Hohmann, Sarah Swagerman, Suzanne C. Heslenfeld, Dirk J. Heuvel, Odile A. Dale, Anders M. Meer, Dennis Erk, Susanne Wee, Nic J. A. Haren, Neeltje E. M. Hoekstra, Pieter J. Ent, Dennis Conrod, Patricia Gur, Ruben C. Geus, Eco J. C. Bonvino, Aurora Erp, Theo G. M. Thomopoulos, Sophia I. Baur Streubel, Ramona Kuntsi, Jonna Walter, Henrik Klein, Marieke Wierenga, Lara M. Kahn, Rene Frodl, Thomas Wittfeld, Katharina Harrison, Ben J. Wolf, Daniel H. Worker, Amanda Krämer, Bernd Wright, Margaret J. Espeseth, Thomas Jiang, Jiyang Gotlib, Ian H. Nyberg, Lars Cannon, Dara M. Yang, Kun Wang, Yang Dima, Danai Hartman, Catharine A. Karolinska Schizophrenia Project (KaSP) Boomsma, Dorret I. Borgwardt, Stefan Mcdonald, Brenna C. Ho, Beng Choon Lagopoulos, Jim Bourque, Josiane Jönsson, Erik G. Brandeis, Daniel Breier, Alan Glahn, David C. Brodaty, Henry Hatton, Sean N. Mataix Cols, David Holmes, Avram J. Salvador, Raymond Temmingh, Henk S. Haan, Lieuwe de Brouwer, Rachel M. Andreassen, Ole A. Caseras, Xavier Joska, John A. Castellanos, Francisco X. Cervenka, Simon Chaim-Avancini, Tiffany M. Paloyelis, Yannis Koops, Sanne Wang, Lei Hosten, Norbert Ching, Christopher R. K. Busatto, Geraldo F. Grabe, Hans Jörgen Conzelmann, Annette Sachdev, Perminder S. Zubicaray, Greig I. Mcdonald, Colm Braber, Anouk Dickie, Erin W. Di Giorgio, Annabella Satterthwaite, Theodore D. Doan, Nhat Trung Rinker, Daniel A. Andreasen, Nancy C. Lebedeva, Irina Dørum, Erlend S. Crone, Eveline A. Hoogman, Martine Fatouros Bergman, Helena Tamnes, Christian K. Grimm, Oliver Ortiz García Foz, Víctor Groenewold, Nynke A. Roffman, Joshua L. Grotegerd, Dominik Gruber, Oliver Tordesillas Gutiérrez, Diana Gruner, Patricia Soriano Mas, Carles Pauli, Paul Lee, Won Hee Gur, Rachel E. Franke, Barbara Lázaro, Luisa Wen, Wei Heinz, Andreas Walton, Esther Howells, Fleur M. Sarró, Salvador Hulshoff Pol, Hilleke E. Stein, Dan J. Huyser, Chaim Jahanshad, Neda Weber, Bernd James, Anthony Rosa, Pedro G. P. Veer, Ilya M. Saykin, Andrew J. McIntosh, Andrew M. Jernigan, Terry L. Hickie, Ian B. Kalnin, Andrew Bargalló Alabart, Núria Kanai, Ryota Andersson, Micael Lesch, Klaus-Peter Thompson, Paul M. Tomyshev, Alexander S. Lochner, Christine Veltman, Dick J. Machielsen, Marise W. J. Maingault, Sophie Banaschewski, Tobias Martin, Nicholas G. Strike, Lachlan T. Yoncheva, Yulyia Turner, Jessica A. Crivello, Fabrice Pergola, Giulio Martínez Zalacaín, Ignacio Koenders, Laura McMahon, Katie L. Voineskos, Aristotle McPhilemy, Genevieve Menchón Magriñá, José Manuel Medland, Sarah E. Calhoun, Vincent Wassink, Thomas H. Baumeister, Sarah Meyer Lindenberg, Andreas |
Keywords: | Escorça cerebral Envelliment Cerebral cortex Aging |
Issue Date: | 17-Feb-2021 |
Publisher: | Wiley |
Abstract: | Delineating the association of age and cortical thickness in healthy individuals is critical given the association of cortical thickness with cognition and behavior. Previous research has shown that robust estimates of the association between age and brain morphometry require large-scale studies. In response, we used cross-sectional data from 17,075 individuals aged 3-90 years from the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to infer age-related changes in cortical thickness. We used fractional polynomial (FP) regression to quantify the association between age and cortical thickness, and we computed normalized growth centiles using the parametric Lambda, Mu, and Sigma method. Interindividual variability was estimated using meta-analysis and one-way analysis of variance. For most regions, their highest cortical thickness value was observed in childhood. Age and cortical thickness showed a negative association; the slope was steeper up to the third decade of life and more gradual thereafter; notable exceptions to this general pattern were entorhinal, temporopolar, and anterior cingulate cortices. Interindividual variability was largest in temporal and frontal regions across the lifespan. Age and its FP combinations explained up to 59% variance in cortical thickness. These results may form the basis of further investigation on normative deviation in cortical thickness and its significance for behavioral and cognitive outcomes. |
Note: | Reproducció del document publicat a: https://doi.org/10.1002/hbm.25364 |
It is part of: | Human Brain Mapping, 2022, vol.43, num. 1, p. 431-451 |
URI: | http://hdl.handle.net/2445/174673 |
Related resource: | https://doi.org/10.1002/hbm.25364 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
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