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http://hdl.handle.net/2445/174767
Title: | Effectiveness and Efficiency of Drug Eluting Stents |
Author: | Moreu, José Hernández, José María Ruiz-Nodar, Juan M. Vázquez, Nicolás Cequier Fillat, Àngel R. Fernández-Vázquez, Felipe Crespo Palomo, Carlos |
Keywords: | Malalties coronàries Pròtesis de Stent Medicaments Coronary diseases Stents (Surgery) Drugs |
Issue Date: | 16-Mar-2012 |
Publisher: | IntechOpen |
Abstract: | Coronary artery disease (CAD), also known as ischemic heart disease (IHD) and coronary heart disease (CHD), is caused by the narrowing (stenosis) of one or more coronary arteries, due to atherosclerosis, restricting blood flow and reducing the supply of oxygen to the heart muscle. Transient shortages in blood flow and oxygen lead to angina pectoris and chest pain, which may radiate to the left shoulder, arms, neck, back or jaw. Stable angina symptoms do not tend to progress in intensity over time. More seriously, the rupturing of an atherosclerotic plaque (causing a thrombotic occlusion) and stenosis of the vessel can result in acute myocardial infarction (AMI) due to a critical reduction in the blood supply to the heart muscle (myocardial ischemia). High levels of morbidity and mortality associated with this infarction are a consequence of ischemia. It is vital to promptly re-establish coronary blood flow after an infarction, because sustained ischemic damages and injuries to the heart muscle may lead to sudden death or heart failure. In addition to infarction, acute symptomatic manifestations of ischemic heart disease include unstable angina, and less common conditions such as cardiogenic shock and sudden death (Thygesen, 2007)... |
Note: | Reprodució del document publicat a: https://doi.org/10.5772/30689 |
It is part of: | Chapter 10 in: Gaze, David C. 2012. Coronary Artery Disease: Current Concepts in Epidemiology, Pathophysiology, Diagnostics and Treatment. IntechOpen. ISBN: 978-953-51-6890-4. DOI: 10.5772/2448. pp. 186-212 |
URI: | http://hdl.handle.net/2445/174767 |
Related resource: | https://doi.org/10.5772/30689 |
Appears in Collections: | Llibres / Capítols de llibre (Genètica, Microbiologia i Estadística) Llibres / Capítols de llibre (Ciències Clíniques) |
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