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DC Field | Value | Language |
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dc.contributor.author | Lugo, Vera M. | - |
dc.contributor.author | Garmendia, Onintza | - |
dc.contributor.author | Suarez Girón, Monique | - |
dc.contributor.author | Torres, Marta | - |
dc.contributor.author | Vázquez Polo, Francisco J. | - |
dc.contributor.author | Negrín, Miguel A. | - |
dc.contributor.author | Moraleda, Anabel | - |
dc.contributor.author | Roman, Mariana | - |
dc.contributor.author | Puig, Marta | - |
dc.contributor.author | Ruiz, Concepción | - |
dc.contributor.author | Egea, Carlos | - |
dc.contributor.author | Masa, Juan F. | - |
dc.contributor.author | Farré Ventura, Ramon | - |
dc.contributor.author | Montserrat Canal, José Ma. | - |
dc.date.accessioned | 2021-03-19T10:40:28Z | - |
dc.date.available | 2021-03-19T10:40:28Z | - |
dc.date.issued | 2019-10-24 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | http://hdl.handle.net/2445/175412 | - |
dc.description.abstract | Introduction: Obstructive sleep apnea (OSA) is a prevalent disease associated with significant morbidity and high healthcare costs. Information and communication technology could offer cost-effective management options. Objectives: To evaluate an out-of-hospital Virtual Sleep Unit (VSU) based on telemedicine to manage all patients with suspected OSA, including those with and without continuous positive airway pressure (CPAP) therapy.Methods: This was an open randomized controlled trial. Patients with suspected OSA were randomized to hospital routine (HR) or VSU groups to compare the clinical improvement and cost-effectiveness in a non-inferiority analysis. Improvement was assessed by changes in the Quebec Sleep Questionnaire (QSQ), EuroQol (EQ-5D and EQ-VAS), and Epworth Sleepiness Scale (ESS). The follow-up was 3 months. Cost-effectiveness was assessed by a Bayesian analysis based on quality-adjusted life-years (QALYs).Results: The HR group (n: 92; 78% OSA, 57% CPAP) compared with the VSU group (n: 94; 83% OSA, 43% CPAP) showed: CPAP compliance was similar in both groups, the QSQ social interactions domain improved significantly more in the HR group whereas the EQ-VAS improved more in the VSU group. Total and OSA-related costs were lower in the VSU group than the HR. The Bayesian cost-effectiveness analysis showed that VSU was cost-effective for a wide range of willingness to pay for QALYs. Conclusions: The VSU offered a cost-effective means of improving QALYs than HR. However, the assessment of its clinical improvement was influenced by the choice of the questionnaire; hence, additional measurements of clinical improvement are needed. Our findings indicate that VSU could help with the management of many patients, irrespective of CPAP use. | - |
dc.format.extent | 15 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Public Library of Science (PLoS) | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1371/journal.pone.0224069 | - |
dc.relation.ispartof | PLoS One, 2019, vol. 14, num. 10, p. e0224069 | - |
dc.relation.uri | https://doi.org/10.1371/journal.pone.0224069 | - |
dc.rights | cc-by (c) Lugo, Vera M. et al., 2019 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | - |
dc.source | Articles publicats en revistes (Biomedicina) | - |
dc.subject.classification | Síndromes d'apnea del son | - |
dc.subject.classification | Qualitat de vida | - |
dc.subject.classification | Telecomunicació en medicina | - |
dc.subject.other | Sleep apnea syndromes | - |
dc.subject.other | Quality of life | - |
dc.subject.other | Telecommunication in medicine | - |
dc.title | Comprehensive management of obstructive sleep apnea by telemedicine: Clinical improvement and cost-effectiveness of a Virtual Sleep Unit. A randomized controlled trial | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 694936 | - |
dc.date.updated | 2021-03-19T10:40:28Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 31647838 | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Medicina) Articles publicats en revistes (Biomedicina) |
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694936.pdf | 1.08 MB | Adobe PDF | View/Open |
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