Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/175633
Title: | Morphotropism and 'Quasi-Isostructurality' in the Three High Z′ Concomitant Polymorphs of Efinaconazole |
Author: | Prohens López, Rafael Barbas Cañero, Rafael Font Bardia, Ma. Mercedes |
Keywords: | Processos químics Estructura cristal·lina (Sòlids) Chemical processes Layer structure (Solids) |
Issue Date: | 26-Apr-2020 |
Publisher: | American Chemical Society |
Abstract: | The crystal structures of the three efinaconazole anhydrous forms have been solved by single-crystal X-ray diffraction showing a very rare case of nearly isostructural polymorphism. The analysis of their crystal structures revealed that forms I and III are 'quasi-isostructural' polymorphs and are morphotropically related to form II. The identical conformational and supramolecular environment can explain the concomitant polymorphism phenomenon observed for this important active pharmaceutical ingredient. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1021/acs.cgd.0c00586 |
It is part of: | Crystal Growth & Design, 2020, vol. 20, num. 7, p. 4238-4242 |
URI: | http://hdl.handle.net/2445/175633 |
Related resource: | https://doi.org/10.1021/acs.cgd.0c00586 |
ISSN: | 1528-7483 |
Appears in Collections: | Articles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada) |
Files in This Item:
File | Description | Size | Format | |
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709630.pdf | 824.83 kB | Adobe PDF | View/Open |
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