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Title: | Impact of diabetes in patients waiting for invasive cardiac procedures during COVID-19 pandemic |
Author: | Moreno, Raúl Díez, José Luis Diarte, José Antonio Salinas, Pablo Torre Hernández, José María de la Andres Cordón, Juan F. Trillo, Ramiro Alonso Briales, Juan Amat Santos, Ignacio J. Romaguera, Rafael Díaz, José Francisco Vaquerizo, Beatriz Ojeda, Soledad Cruz González, Ignacio Morena Salas, Daniel Pérez de Prado, Armando Sarnago, Fernando Portero, Pilar Gutierrez Barrios, Alejandro Alfonso, Fernando Bosch, Eduard Pinar, Eduardo Ruiz Arroyo, José Ramón Ruiz Quevedo, Valeriano Jiménez Mazuecos, Jesús Lozano, Fernando Rumoroso, José Ramón Novo, Enrique Irazusta, Francisco J. García del Blanco, Bruno Moreu, José Ballesteros Pradas, Sara M. Frutos, Araceli Villa, Manuel Alegría Barrero, Eduardo Lázaro, Rosa Paredes, Emilio |
Keywords: | Diabetis COVID-19 Cardiologia Mortalitat Diabetes COVID-19 Cardiology Mortality |
Issue Date: | 23-Mar-2021 |
Publisher: | Springer Nature |
Abstract: | Background: During COVID-19 pandemic, elective invasive cardiac procedures (ICP) have been frequently cancelled or postponed. Consequences may be more evident in patients with diabetes. Objectives: The objective was to identify the peculiarities of patients with DM among those in whom ICP were cancelled or postponed due to the COVID-19 pandemic, as well as to identify subgroups in which the influence of DM has higher impact on the clinical outcome. Methods: We included 2,158 patients in whom an elective ICP was cancelled or postponed during COVID-19 pandemic in 37 hospitals in Spain. Among them, 700 (32.4%) were diabetics. Patients with and without diabetes were compared. Results: Patients with diabetes were older and had a higher prevalence of other cardiovascular risk factors, previous cardiovascular history and co-morbidities. Diabetics had a higher mortality (3.0% vs. 1.0%; p = 0.001) and cardiovascular mortality (1.9% vs. 0.4%; p = 0.001). Differences were especially important in patients with valvular heart disease (mortality 6.9% vs 1.7% [p < 0.001] and cardiovascular mortality 4.9% vs 0.9% [p = 0.002] in patients with and without diabetes, respectively). In the multivariable analysis, diabetes remained as an independent risk factor both for overall and cardiovascular mortality. No significant interaction was found with other clinical variables. Conclusion: Among patients in whom an elective invasive cardiac procedure is cancelled or postponed during COVID-19 pandemic, mortality and cardiovascular mortality is higher in patients with diabetes, irrespectively on other clinical conditions. These procedures should not be cancelled in patients with diabetes. |
Note: | Reproducció del document publicat a: https://doi.org/10.1186/s12933-021-01261-2 |
It is part of: | Cardiovascular Diabetology, 2021, vol. 20 |
URI: | http://hdl.handle.net/2445/176046 |
Related resource: | https://doi.org/10.1186/s12933-021-01261-2 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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