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Title: | Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital |
Author: | García-Basteiro, Alberto L. Moncunill, Gemma Tortajada, Marta Vidal, Marta Guinovart, Caterina Jiménez, Alfons Santano, Rebeca Sanz, Sergi Méndez, Susana Llupià Garcia, Anna Aguilar, Ruth Alonso, Selena Barrios, Diana Carolis, Carlo Cisteró, Pau Chóliz, Eugenia Cruz, Angeline Fochs, Silvia Jairoce, Chenjerai Hecht, Jochen Lamoglia-Puig, Montserrat Martínez Yoldi, Miguel Julián Mitchell, Robert A. Ortega, Natalia Pey, Nuria Puyol, Laura Ribes, Marta Rosell, Neus Sotomayor, Patricia Torres, Sara Williams, Sara Barroso, Sonia Vilella i Morató, Anna Muñoz Gutiérrez, José Trilla García, Antoni Varela, Pilar Mayor Aparicio, Alfredo Gabriel Dobaño, Carlota, 1969- |
Keywords: | SARS-CoV-2 Immunoglobulines Epidemiologia SARS-CoV-2 Immunoglobulins Epidemiology |
Issue Date: | 8-Jul-2020 |
Publisher: | Nature Publishing Group |
Abstract: | Health care workers (HCW) are a high-risk population to acquire SARS-CoV-2 infection from patients or other fellow HCW. This study aims at estimating the seroprevalence against SARS-CoV-2 in a random sample of HCW from a large hospital in Spain. Of the 578 participants recruited from 28 March to 9 April 2020, 54 (9.3%, 95% CI: 7.1-12.0) were seropositive for IgM and/or IgG and/or IgA against SARS-CoV-2. The cumulative prevalence of SARS-CoV-2 infection (presence of antibodies or past or current positive rRT-PCR) was 11.2% (65/578, 95% CI: 8.8-14.1). Among those with evidence of past or current infection, 40.0% (26/65) had not been previously diagnosed with COVID-19. Here we report a relatively low seroprevalence of antibodies among HCW at the peak of the COVID-19 epidemic in Spain. A large proportion of HCW with past or present infection had not been previously diagnosed with COVID-19, which calls for active periodic rRT-PCR testing in hospital settings. |
Note: | Reproducció del document publicat a: https://doi.org/10.1038/s41467-020-17318-x |
It is part of: | Nature Communications, 2020, vol. 11, num. 1, p. 3500 |
URI: | http://hdl.handle.net/2445/176139 |
Related resource: | https://doi.org/10.1038/s41467-020-17318-x |
ISSN: | 2041-1723 |
Appears in Collections: | Articles publicats en revistes (ISGlobal) Articles publicats en revistes (Medicina) |
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