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http://hdl.handle.net/2445/176178
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DC Field | Value | Language |
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dc.contributor.author | Josa Laorden, Claudia | - |
dc.contributor.author | Crestelo Vieitez, Anxela | - |
dc.contributor.author | García Andreu, María | - |
dc.contributor.author | Rubio-Rivas, Manuel | - |
dc.contributor.author | Sánchez, Marcos | - |
dc.contributor.author | Toledo Samaniego, Neera | - |
dc.contributor.author | Arnalich Fernández, Francisco | - |
dc.contributor.author | Iguaran Bermudez, Rosario | - |
dc.contributor.author | Fonseca Aizpuru, Eva | - |
dc.contributor.author | Vargas Núñez, Juan Antonio | - |
dc.contributor.author | Pesqueira Fontan, Paula Maria | - |
dc.contributor.author | Serrano Ballesteros, Jorge | - |
dc.contributor.author | Freire Castro, Santiago | - |
dc.contributor.author | Pestaña Fernández, Melani | - |
dc.contributor.author | Viana García, Alba | - |
dc.contributor.author | Nuñez Rodriguez, Victoria | - |
dc.contributor.author | Giner Galvañ, Vicente | - |
dc.contributor.author | Carrasco Sánchez, Francisco | - |
dc.contributor.author | Hernández Milián, Almudena | - |
dc.contributor.author | Cobos Siles, Marta | - |
dc.contributor.author | Napal Lecumberri, Jose | - |
dc.contributor.author | Herrero García, Virginia | - |
dc.contributor.author | Pascual Pérez, Maria | - |
dc.contributor.author | Millán Núñez-Cortés, Jesús | - |
dc.contributor.author | Casas Rojo, José | - |
dc.contributor.author | SEMI-COVID-19 Network | - |
dc.date.accessioned | 2021-04-12T09:44:47Z | - |
dc.date.available | 2021-04-12T09:44:47Z | - |
dc.date.issued | 2021-02-25 | - |
dc.identifier.uri | http://hdl.handle.net/2445/176178 | - |
dc.description.abstract | There is some evidence that male gender could have a negative impact on the prognosis and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aim of the present study was to compare the characteristics of coronavirus disease 2019 (COVID-19) between hospitalized men and women with confirmed SARS-CoV-2 infection. This multicenter, retrospective, observational study is based on the SEMI-COVID-19 Registry. We analyzed the differences between men and women for a wide variety of demographic, clinical, and treatment variables, and the sex distribution of the reported COVID-19 deaths, as well as intensive care unit (ICU) admission by age subgroups. This work analyzed 12,063 patients (56.8% men). The women in our study were older than the men, on average (67.9 vs. 65.7 years; p < 001). Bilateral condensation was more frequent among men than women (31.8% vs. 29.9%; p = 0.007). The men needed non-invasive and invasive mechanical ventilation more frequently (5.6% vs. 3.6%, p < 0.001, and 7.9% vs. 4.8%, p < 0.001, respectively). The most prevalent complication was acute respiratory distress syndrome, with severe cases in 19.9% of men (p < 0.001). In men, intensive care unit admission was more frequent (10% vs. 6.1%; p < 0.001) and the mortality rate was higher (23.1% vs. 18.9%; p < 0.001). Regarding mortality, the differences by gender were statistically significant in the age groups from 55 years to 89 years of age. A multivariate analysis showed that female sex was significantly and independently associated with a lower risk of mortality in our study. Male sex appears to be related to worse progress in COVID-19 patients and is an independent prognostic factor for mortality. In order to fully understand its prognostic impact, other factors associated with sex must be considered. | - |
dc.format.extent | 21 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/jcm10050899 | - |
dc.relation.ispartof | Journal of Clinical Medicine, 2021, vol. 10, num. 5 | - |
dc.relation.uri | https://doi.org/10.3390/jcm10050899 | - |
dc.rights | cc by (c) Josa Laorden et al., 2021 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Factors sexuals en les malalties | - |
dc.subject.classification | SARS-CoV-2 | - |
dc.subject.classification | COVID-19 | - |
dc.subject.classification | Espanya | - |
dc.subject.other | Sex factors in disease | - |
dc.subject.other | SARS-CoV-2 | - |
dc.subject.other | COVID-19 | - |
dc.subject.other | Spain | - |
dc.title | Gender-Based Differences by Age Range in Patients Hospitalized with COVID-19: A Spanish Observational Cohort Study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2021-04-08T07:46:29Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 33668766 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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jcm-10-00899-v3.pdf | 1.82 MB | Adobe PDF | View/Open |
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