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http://hdl.handle.net/2445/178163
Title: | Human Translational Research in Psoriasis Using CLA+ T Cells |
Author: | Ruiz Romeu, Ester Santamaria Babí, Luis F. |
Keywords: | Psoriasi Limfòcits Psoriasis Lymphocytes |
Issue Date: | Jul-2017 |
Publisher: | IntechOpen |
Abstract: | Focusing on the study of human memory CLA+ T cells to understand psoriasis pathology constitutes an innovative approach to explore the pathological mechanism of this chronic cutaneous inflammatory disease. CLA+ T cells can be considered peripheral cell biomarkers in the study of T-cell mediated human skin diseases. During the last few years, new evidences have been found that link streptococcal infection with IL-17 response in psoriasis by studying the interaction between Streptococcus pyogenes with CLA+ T cells and autologous epidermal cells. S. pyogenes constitutes the best clinically characterized trigger of psoriasis and by exploring its effect on CLA+ T cells and epidermal cells in psoriasis may allow understanding psoriasis by using patient’s clinical samples ex vivo. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.5772/67815 |
It is part of: | Chapter 4 in: Chiriac, Anca. 2017. Psoriasis. IntechOpen. ISBN: 978-953-51-4763-3. DOI: 10.5772/65196. pp: 62-74. |
URI: | http://hdl.handle.net/2445/178163 |
Related resource: | http://dx.doi.org/10.5772/67815 |
Appears in Collections: | Llibres / Capítols de llibre (Biologia Cel·lular, Fisiologia i Immunologia) |
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