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http://hdl.handle.net/2445/178626
Title: | Perivascular epitheliod cell tumors: Study of three gynecological cases |
Author: | Nicolás, Inmaculada Fusté, Pere Saco, Adela Ordi i Majà, Jaume Torné Bladé, Aureli |
Keywords: | Tumors Càncer ginecològic Tumors Gynecologic cancer |
Issue Date: | 9-Jan-2019 |
Publisher: | Elsevier España |
Abstract: | Antecedents: Perivascular epitheliod cell tumor (PEComa) is a rare mesenchymal tumor. They are rare in the field of gynecology, which makes them difficult to consider as a possible diagnostic. We aim to contribute with our experience to ease clinical practice to others gynecologists. Patients and methods: We contribute to literature with three gynecological cases; uterine, vaginal and retroperitoneal PEComas. Results: The uterine and vaginal PEComa, have required surgical treatment, and are free of disease at 9 and 5 months respectively. The retroperitoneal PEComa has recurred at 72 months of follow-up in form of retroperitoneal mass and pulmonary lymphangioleomyomatosis, continues treatment with sirolimus with good tolerance and partial response. Discussion: Given the scarcity of cases, the literature consists of case reports and mini-reviews. Some authors have categorized the PEComas based on prognostic factors, but there is no agreement regarding the follow-up and treatment. 18F-FDG-PET/CT can help characterize these lesions. The surgery is the standard. In recurrent or malignant cases, there is a lack of evidence regarding chemotherapy and radiotherapy. New therapies with inhibitory m-TOR open a hopeful therapeutic window. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1016/j.medcli.2019.01.009 |
It is part of: | Medicina Clinica, 2019, vol. 153, num. 2, p. 83-87 |
URI: | http://hdl.handle.net/2445/178626 |
Related resource: | https://doi.org/10.1016/j.medcli.2019.01.009 |
ISSN: | 0025-7753 |
Appears in Collections: | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) Articles publicats en revistes (Fonaments Clínics) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (ISGlobal) |
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