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http://hdl.handle.net/2445/178957
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DC Field | Value | Language |
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dc.contributor.author | Kennington, Stuart C. D. | - |
dc.contributor.author | Teloxa, Saul F. | - |
dc.contributor.author | Mellado Hidalgo, Miguel | - |
dc.contributor.author | Galeote, Oriol | - |
dc.contributor.author | Puddu, Sabrina | - |
dc.contributor.author | Bellido, Marina | - |
dc.contributor.author | Romea, Pedro | - |
dc.contributor.author | Urpí Tubella, Fèlix | - |
dc.contributor.author | Aullón López, Gabriel | - |
dc.contributor.author | Font Bardia, Ma. Mercedes | - |
dc.date.accessioned | 2021-07-09T13:04:31Z | - |
dc.date.available | 2021-07-09T13:04:31Z | - |
dc.date.issued | 2021-07-05 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | http://hdl.handle.net/2445/178957 | - |
dc.description.abstract | A direct and asymmetric aldol reaction of N-acylthiazinanethiones with aromatic aldehydes catalyzed by chiralnickel(II) complexes is reported. The reaction gives thecorresponding O-TIPS-protected anti-aldol adducts in highyields and with remarkable stereocontrol and atom economy.Furthermore, the straightforward removal of the achiralscaffold provides enantiomerically pure intermediates ofsynthetic interest, which involve precursors for anti-a-amino-b-hydroxy anda,b-dihydroxy carboxylic derivatives. Theoret-ical calculations explain the observed high stereocontrol. | - |
dc.format.extent | 6 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Wiley-VCH | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1002/anie.202104352 | - |
dc.relation.ispartof | Angewandte Chemie-International Edition, 2021, vol. 60, num. 28, p. 15307-15312 | - |
dc.relation.uri | https://doi.org/10.1002/anie.202104352 | - |
dc.rights | cc-by-nc-nd (c) Kennington et al, 2021 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.source | Articles publicats en revistes (Química Inorgànica i Orgànica) | - |
dc.subject.classification | Reacció aldòlica | - |
dc.subject.classification | Síntesi asimètrica | - |
dc.subject.classification | Níquel | - |
dc.subject.other | Aldol reaction | - |
dc.subject.other | Asymmetric synthesis | - |
dc.subject.other | Nickel | - |
dc.title | Direct and enantioselective aldol reactions catalyzed by chiral nickel(II) complexes | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 713060 | - |
dc.date.updated | 2021-07-09T13:04:31Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 33872449 | - |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
Files in This Item:
File | Description | Size | Format | |
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713060.pdf | 1.61 MB | Adobe PDF | View/Open |
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