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Title: | COVID-19 in the tonsillectomised population |
Author: | Capriotti, Vincenzo Mattioli, Francesco Guida, Francesco Marcuzzo, Alberto Vito Lo Manto, Alfredo Martone, Andrea Molinari, Giulia Fabbris, Cristoforo Menegaldo, Anna Calvanese, Leonardo Latini, Gino Cingolani, Cristina Gradoni, Paolo Boscolo Nata, Francesca De Sisti, Clelia Selle, Vittorio Leone, Giordano Indelicato, Pietro Pilolli, Francesco Mevio, Niccolò Roncoroni, Luca Papi, Simona Meschiari, Marianna Tominz, Riccardo D’ascanio, Luca Dragonetti, Alberto Torelli, Lucio Trenti, Loris Spinato, Giacomo Boscolo Rizzo, Paolo Bussi, Mario Cossarizza, Andrea Presutti, Livio Tirelli, Giancarlo |
Keywords: | COVID-19 SARS-CoV-2 Amígdales COVID-19 SARS-CoV-2 Tonsils |
Issue Date: | 1-Jun-2021 |
Publisher: | Pacini Editore |
Abstract: | Objective: Interactions between SARS-CoV-2 and pharyngeal associated lymphoid tissue are thought to influence the manifestations of COVID-19. We aimed to determine whether a previous history of tonsillectomy, as a surrogate indicator of a dysfunctional pharyngeal associated lymphoid tissue, could predict the presentation and course of COVID-19. Methods: Multicentric cross-sectional observational study involving seven hospitals in Northern and Central Italy. Data on the clinical course and signs and symptoms of the infection were collected from 779 adults who tested positive for SARS-CoV-2, and analysed in relation to previous tonsillectomy, together with demographic and anamnestic data. Results: Patients with previous tonsillectomy showed a greater risk of fever, temperature higher than 39°C, chills and malaise. No significant differences in hospital admissions were found. Conclusions: A previous history of tonsillectomy, as a surrogate indicator of immunological dysfunction of the pharyngeal associated lymphoid tissue, could predict a more intense systemic manifestation of COVID-19. These results could provide a simple clinical marker to discriminate suspected carriers and to delineate more precise prognostic models. |
Note: | Reproducció del document publicat a: https://doi.org/10.14639/0392-100X-N1436 |
It is part of: | Acta Otorhinolaryngologica Italica, 2021, vol. 41, num. 3, p. 197-205 |
URI: | http://hdl.handle.net/2445/179339 |
Related resource: | https://doi.org/10.14639/0392-100X-N1436 |
ISSN: | 1827-675X |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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1436-Article Text-13288-2-10-20210707.pdf | 142.68 kB | Adobe PDF | View/Open |
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