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Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/179354
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dc.contributor.authorSubirós Funosas, Ramon-
dc.contributor.authorCheuk Lam Ho, Vivian-
dc.contributor.authorBarth, Nicole D.-
dc.contributor.authorMendive Tapia, Lorena-
dc.contributor.authorPappalardo, Morena-
dc.contributor.authorBarril Alonso, Xavier-
dc.contributor.authorMa, Ruoyu-
dc.contributor.authorZhang, Cheng-Bin-
dc.contributor.authorQian, Bin-Zhi-
dc.contributor.authorSintes Marcos, Miquel-
dc.contributor.authorGhashghaei, Ouldouz-
dc.contributor.authorLavilla Grífols, Rodolfo-
dc.contributor.authorVendrell, Marc-
dc.date.accessioned2021-07-22T11:47:36Z-
dc.date.available2021-07-22T11:47:36Z-
dc.date.issued2020-01-20-
dc.identifier.issn2041-6520-
dc.identifier.urihttp://hdl.handle.net/2445/179354-
dc.description.abstractKeratin 1 (KRT1) is overexpressed in squamous carcinomas and associated with aggressive pathologies in breast cancer. Herein we report the design and preparation of the first Trp-based red fluorogenic amino acid, which is synthetically accessible in a few steps and displays excellent photophysical properties, and its application in a minimally-disruptive labelling strategy to prepare a new fluorogenic cyclopeptide for imaging of KRT1+ cells in whole intact tumour tissues.-
dc.format.extent7 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherRoyal Society of Chemistry-
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1039/C9SC05558D-
dc.relation.ispartofChemical Science, 2020, vol. 11, p. 1368-1374-
dc.relation.urihttps://doi.org/10.1039/C9SC05558D-
dc.rightscc-by (c) Subirós Funosas, Ramon et al., 2020-
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)-
dc.subject.classificationPèptids-
dc.subject.classificationAminoàcids-
dc.subject.classificationApoptosi-
dc.subject.otherPeptides-
dc.subject.otherAmino acids-
dc.subject.otherApoptosis-
dc.titleFluorogenic Trp(redBODIPY) cyclopeptide targeting keratin 1 for imaging of aggressive carcinomas-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.identifier.idgrec695128-
dc.date.updated2021-07-22T11:47:36Z-
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/771443/EU//DYNAFLUORS-
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/716379/EU//MetResistance-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.pmid34123261-
Appears in Collections:Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

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