Please use this identifier to cite or link to this item:
Title: Zoonotic Abbreviata caucasica in wild chimpanzees (Pan troglodytes verus) from Senegal
Author: Laidoudi, Younes
Medkour, Hacène
Latrofa, Maria Stefania
Davoust, Bernard
Diatta, Georges
Sokhna, Cheikh
Barciela, Amanda
Hernandez-Aguilar, Adriana R.
Raoult, Didier
Otranto, Domenico
Mediannikov, Oleg
Keywords: Nematodes
Issue Date: 27-Jun-2020
Publisher: MDPI
Abstract: Abbreviata caucasica (syn. Physaloptera mordens) has been reported in human and various non-human primates including great apes. The identification of this nematode is seldom performed and relies on egg characterization at the coproscopy, in the absence of any molecular tool. Following the recovery of two adult females of A. caucasica from the feces of wild Senegalese chimpanzees, morphometric characteristics were reported and new data on the width of the esophagus (0.268-0.287 mm) and on the cuticle structure (0.70-0.122 mm) were provided. The molecular characterization of a set of mitochondrial (cox1, 16S rRNA, 12S rRNA) and nuclear (18S rRNA and ITS2) partial genes was performed. Our phylogenetic analysis indicates for the first time that A. caucasica is monophyletic with Physaloptera species. A novel molecular tool was developed for the routine diagnosis of A. caucasica and the surveillance of Nematoda infestations. An A. caucasica-specific qPCR targeting the 12S gene was assessed. The assay was able to detect up to 1.13 × 10−3 eggs/g of fecal matter irrespective of its consistency, with an efficiency of 101.8% and a perfect adjustment (R2 = 0.99). The infection rate by A. caucasica in the chimpanzee fecal samples was 52.08%. Only 6.19% of the environmental samples were positive for nematode DNA and any for A. caucasica. Our findings indicate the need for further studies to clarify the epidemiology, circulation, life cycle, and possible pathological effects of this infestation using the molecular tool herein developed.
Note: Reproducció del document publicat a:
It is part of: Pathogens, 2020, vol. 9, num. 7, p. 517
Related resource:
ISSN: 2076-0817
Appears in Collections:Articles publicats en revistes (Psicologia Social i Psicologia Quantitativa)

Files in This Item:
File Description SizeFormat 
709816.pdf3.48 MBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons