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Title: Modified siRNAs for the study of the PAZ domain
Author: Somoza, Álvaro
Terrazas Martínez, Montserrat
Eritja i Casadellà, Ramon
Keywords: RNA
Fixació de proteïnes
Modificació química de les proteïnes
Protein binding
Chemical modification of proteins
Issue Date: 19-May-2010
Publisher: Royal Society of Chemistry
Abstract: Chemical modifications aimed at stabilizing the interaction between the 3'-end of siRNAs and the PAZ domain of RISC have been tested for their effect on RNAi activity. Such modifications contribute positively to the stability of siRNAs in human serum.
Note: Versió postprint del document publicat a:
It is part of: Chemical Communications, 2010, vol. 46, p. 4270-4272
Related resource:
ISSN: 1359-7345
Appears in Collections:Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))
Articles publicats en revistes (Química Inorgànica i Orgànica)

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