Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/180001
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Gudiol González, Carlota | - |
dc.contributor.author | Durà Miralles, Xavier | - |
dc.contributor.author | Aguilar Company, Juan | - |
dc.contributor.author | Hernández Jiménez, Pilar | - |
dc.contributor.author | Martínez Cutillas, Marta | - |
dc.contributor.author | Fernández Avilés, Francesc | - |
dc.contributor.author | Machado, Marina | - |
dc.contributor.author | Vázquez López, Lourdes | - |
dc.contributor.author | Martín Dávila, Pilar | - |
dc.contributor.author | Castro, Nathalie de | - |
dc.contributor.author | Abdala, Edson | - |
dc.contributor.author | Sorli, Luisa | - |
dc.contributor.author | Andermann, Tessa M. | - |
dc.contributor.author | Márquez Gómez, Ignacio | - |
dc.contributor.author | Morales, H. | - |
dc.contributor.author | Gabilán, F. | - |
dc.contributor.author | Ayaz, C.M. | - |
dc.contributor.author | Kayaaslan, B. | - |
dc.contributor.author | Aguilar Guisado, Manuela | - |
dc.contributor.author | Herrera, F. | - |
dc.contributor.author | Royo Cebrecos, C. | - |
dc.contributor.author | Peghin, M. | - |
dc.contributor.author | González Rico, C. | - |
dc.contributor.author | Goikoetxea, J. | - |
dc.contributor.author | Salgueira, C. | - |
dc.contributor.author | Silva Pinto, A. | - |
dc.contributor.author | Gutiérrez Gutiérrez, B. | - |
dc.contributor.author | Cuellar, S. | - |
dc.contributor.author | Haidar, G. | - |
dc.contributor.author | Maluquer, Clara | - |
dc.contributor.author | Marin, M. | - |
dc.contributor.author | Pallarès, Natàlia | - |
dc.contributor.author | Carratalà, Jordi | - |
dc.date.accessioned | 2021-09-13T10:44:20Z | - |
dc.date.available | 2021-09-13T10:44:20Z | - |
dc.date.issued | 2021-09-01 | - |
dc.identifier.issn | 0163-4453 | - |
dc.identifier.uri | http://hdl.handle.net/2445/180001 | - |
dc.description.abstract | Background: We aimed to describe the epidemiology, risk factors, and clinical outcomes of co-infections and superinfections in onco-hematological patients with COVID-19. Methods: International, multicentre cohort study of cancer patients with COVID-19. All patients were included in the analysis of co-infections at diagnosis, while only patients admitted at least 48 h were included in the analysis of superinfections. Results: 684 patients were included (384 with solid tumors and 300 with hematological malignancies). Co-infections and superinfections were documented in 7.8% (54/684) and 19.1% (113/590) of patients, respectively. Lower respiratory tract infections were the most frequent infectious complications, most often caused by Streptococcus pneumoniae and Pseudomonas aeruginosa. Only seven patients developed opportunistic infections. Compared to patients without infectious complications, those with infections had worse outcomes, with high rates of acute respiratory distress syndrome, intensive care unit (ICU) admission, and case-fatality rates. Neutropenia, ICU admission and high levels of C-reactive protein (CRP) were independent risk factors for infections. Conclusions: Infectious complications in cancer patients with COVID-19 were lower than expected, affecting mainly neutropenic patients with high levels of CRP and/or ICU admission. The rate of opportunistic infections was unexpectedly low. The use of empiric antimicrobials in cancer patients with COVID-19 needs to be optimized. | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier BV | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1016/j.jinf.2021.07.014 | - |
dc.relation.ispartof | Journal of Infection, 2021, vol. 83, num. 3, p. 306-313 | - |
dc.relation.uri | https://doi.org/10.1016/j.jinf.2021.07.014 | - |
dc.rights | cc by-nc-nd (c) Gudiol González, Carlota et al, 2021 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | COVID-19 | - |
dc.subject.classification | Infeccions oportunistes | - |
dc.subject.classification | Malalts de càncer | - |
dc.subject.other | COVID-19 | - |
dc.subject.other | Opportunistic infections | - |
dc.subject.other | Cancer patients | - |
dc.title | Co-infections and superinfections complicating COVID-19 in cancer patients: A multicentre, international study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2021-09-10T11:45:47Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 34302864 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
PIIS016344532100356X.pdf | 420.55 kB | Adobe PDF | View/Open |
This item is licensed under a
Creative Commons License