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http://hdl.handle.net/2445/180085| Title: | Structural brain correlates in major depression, anxiety disorders and post-traumatic stress disorder: A voxel-based morphometry meta-analysis |
| Author: | Serra Blasco, María Radua, Joaquim Soriano Mas, Carles Gómez Benlloch, Alba Porta Casteràs, Daniel Carulla, Montserrat, 1930- Albajes Eizagirre, Anton Arnone, Danilo Klauser, Paul Canales Rodríguez, Erick Jorge Hilbert, Kevin Wise, Toby Cheng, Yuqui Kandilarova, Sevdalina Mataix Cols, David Vieta i Pascual, Eduard, 1963- Via, Esther Cardoner, N. (Narcís) |
| Keywords: | Psicopatologia Comorbiditat Psychology, Pathological Comorbidity |
| Issue Date: | 11-Jul-2021 |
| Publisher: | Elsevier |
| Abstract: | The high comorbidity of Major Depressive Disorder (MDD), Anxiety Disorders (ANX), and Posttraumatic Stress Disorder (PTSD) has hindered the study of their structural neural correlates. The authors analyzed specific and common grey matter volume (GMV) characteristics by comparing them with healthy controls (HC). The meta-analysis of voxel-based morphometry (VBM) studies showed unique GMV diminutions for each disorder (p < 0.05, corrected) and less robust smaller GMV across diagnostics (p < 0.01, uncorrected). Pairwise comparison between the disorders showed GMV differences in MDD versus ANX and in ANX versus PTSD. These results endorse the hypothesis that unique clinical features characterizing MDD, ANX, and PTSD are also reflected by disorder specific GMV correlates. |
| Note: | Reproducció del document publicat a: https://doi.org/10.1016/j.neubiorev.2021.07.002 |
| It is part of: | Neuroscience & Biobehavioral Reviews, 2021, vol. 129, p. 269-281 |
| URI: | http://hdl.handle.net/2445/180085 |
| Related resource: | https://doi.org/10.1016/j.neubiorev.2021.07.002 |
| ISSN: | 0149-7634 |
| Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) |
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| 1-s2.0-S0149763421003006-main.pdf | 3.96 MB | Adobe PDF | View/Open |
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