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Title: | Sensitivity of cervical cytology in endometrial cancer detection in a tertiary hospital in Spain |
Author: | Frias Gomez, Jon Tovar, Eva Vidal, August Murgui, Lluis Ibáñez, Raquel Peremiquel Trillas, Paula Paytubi Casabona, Sònia Baixeras, Nuria Zanca, Alba Ponce i Sebastià, Jordi Pineda, Marta Brunet, Joan De Sanjosé, Silvia Bosch, F. Xavier Matias-Guiu, Xavier Alemany, Laia Costas, Laura Screenwide Team |
Keywords: | Càncer d'endometri Citodiagnòstic Endometrial cancer Cytodiagnosis |
Issue Date: | 4-Sep-2021 |
Publisher: | Wiley |
Abstract: | Introduction: Cervical cytology is a well-stablished cervical cancer screening method. However, due to the anatomical continuity of the genital tract, it can also detect signs of endometrial disease. Our aim was to estimate the sensitivity of cervical cytology in endometrial cancer detection and prognosis in a large population over a 30-year period in a large academic tertiary hospital in Spain. Methodology: We performed a search for women diagnosed with endometrial cancer from 1990 to 2020, who were surgically treated and had a previous cervical cytology result. Information Technologies Department databases from Bellvitge University Hospital and the Screenwide case-control study's database were used. Cervical cytology results were classified as abnormal when squamous lesions, glandular atypia or malignant cells were identified. Results: Overall, we evaluated 371 women with endometrial cancer and a documented cervical cytology performed within 3 years previous to surgical treatment. Overall, the sensitivity of cervical cytology for endometrial cancer detection was 25.6%. Several clinico-pathological characteristics, such as non-endometrioid histology and a higher stage, were correlated with higher sensitivity. |
Note: | Reproducció del document publicat a: https://doi.org/10.1002/cam4.4217 |
It is part of: | Cancer Medicine, 2021 |
URI: | http://hdl.handle.net/2445/180087 |
Related resource: | https://doi.org/10.1002/cam4.4217 |
ISSN: | 2045-7634 |
Appears in Collections: | Articles publicats en revistes (Patologia i Terapèutica Experimental) Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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