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http://hdl.handle.net/2445/180349
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DC Field | Value | Language |
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dc.contributor.author | Berenguer, J. (Joaquín Berenguer Lapuerta) | - |
dc.contributor.author | Borobia, Alberto M. | - |
dc.contributor.author | Ryan, Pablo | - |
dc.contributor.author | Rodríguez Baño, Jesús | - |
dc.contributor.author | Bellón, José M. | - |
dc.contributor.author | Jarrín Vera, Inmaculada | - |
dc.contributor.author | Carratalà, Jordi | - |
dc.contributor.author | Pachón, Jerónimo | - |
dc.contributor.author | Carcas Sansuán, Antonio J. | - |
dc.contributor.author | Yllescas, María | - |
dc.contributor.author | Arribas, José Ramón | - |
dc.contributor.author | Smithson Amat, Alejandro | - |
dc.contributor.author | COVID-19 Spain Study Group | - |
dc.contributor.author | COVID HULP Study Group | - |
dc.date.accessioned | 2021-10-01T16:33:36Z | - |
dc.date.available | 2021-10-01T16:33:36Z | - |
dc.date.issued | 2021-02-25 | - |
dc.identifier.issn | 0040-6376 | - |
dc.identifier.uri | http://hdl.handle.net/2445/180349 | - |
dc.description.abstract | Participants: Derivation (DC) and external validation (VC) cohorts were obtained from multicentre and single-centre databases, including 4035 and 2126 patients with confirmed COVID-19, respectively. Interventions: Prognostic variables were identified using multivariable logistic regression. Main outcome measures: 30-day mortality. Results: Patients' characteristics in the DC and VC were median age 70 and 61 years, male sex 61.0% and 47.9%, median time from onset of symptoms to admission 5 and 8 days, and 30-day mortality 26.6% and 15.5%, respectively. Age, low age-adjusted saturation of oxygen, neutrophil-to-lymphocyte ratio, estimated glomerular filtration rate by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, dyspnoea and sex were the strongest predictors of mortality. Calibration and discrimination were satisfactory with an area under the receiver operating characteristic curve with a 95% CI for prediction of 30-day mortality of 0.822 (0.806-0.837) in the DC and 0.845 (0.819-0.870) in the VC. A simplified score system ranging from 0 to 30 to predict 30-day mortality was also developed. The risk was considered to be low with 0-2 points (0%-2.1%), moderate with 3-5 (4.7%-6.3%), high with 6-8 (10.6%-19.5%) and very high with 9-30 (27.7%-100%). Conclusions: A simple prediction score, based on readily available clinical and laboratory data, provides a useful tool to predict 30-day mortality probability with a high degree of accuracy among hospitalised patients with COVID-19. | - |
dc.format.extent | 10 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | BMJ Publishing Group | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1136/thoraxjnl-2020-216001 | - |
dc.relation.ispartof | Thorax, 2021, vol. 76, num. 9, p. 920-929 | - |
dc.relation.uri | https://doi.org/10.1136/thoraxjnl-2020-216001 | - |
dc.rights | (c) BMJ Publishing Group, 2021 | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | COVID-19 | - |
dc.subject.classification | Teoria de la predicció | - |
dc.subject.classification | Diagnòstic | - |
dc.subject.other | COVID-19 | - |
dc.subject.other | Prediction theory | - |
dc.subject.other | Diagnosis | - |
dc.title | Development and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score. | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 708274 | - |
dc.date.updated | 2021-10-01T16:33:37Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 33632764 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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708274.pdf | 826.34 kB | Adobe PDF | View/Open |
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