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http://hdl.handle.net/2445/181865
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DC Field | Value | Language |
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dc.contributor.author | Fernández Delgado, Lucía | - |
dc.contributor.author | Càmara, Jordi | - |
dc.contributor.author | González Díaz, Aida | - |
dc.contributor.author | Grau, Immaculada | - |
dc.contributor.author | Shoji, Hisashi | - |
dc.contributor.author | Tubau, Fe | - |
dc.contributor.author | Martí, Sara | - |
dc.contributor.author | Domínguez Luzón, Ma. Ángeles (María Ángeles) | - |
dc.contributor.author | Carratalà, Jordi | - |
dc.contributor.author | Yuste, Jose | - |
dc.contributor.author | Ardanuy, Carmen | - |
dc.date.accessioned | 2021-12-16T18:09:28Z | - |
dc.date.available | 2021-12-16T18:09:28Z | - |
dc.date.issued | 2021-10-28 | - |
dc.identifier.issn | 2076-2607 | - |
dc.identifier.uri | http://hdl.handle.net/2445/181865 | - |
dc.description.abstract | We studied changes in serotype distribution and antimicrobial susceptibility in adult pneumococcal pneumonia in Spain (2011-2019). Among 895 pneumococci collected (433 bacteremic [BPP] and 462 non-bacteremic [non-BPP]), serotypes 3 (17%), 19A (10%), 8 (6.7%) and 11A (6.7%) were the most frequent. Serotypes 16F, 19A and 24F were associated with old people (≥65) and serotypes 4, 7F, 8, 12F and 19F to young adults. Serotypes 12F, 24F and 1 were significantly more frequent in BPP and serotypes 11A, 23A and 19F in non-BPP. Amoxicillin resistance was higher in non-BPP (17% vs. 11%) while penicillin non-susceptibility (37% vs. 24%) and macrolide resistance (29% vs. 14%) were higher in older adults. In the period 2017-2019, the vaccine coverages were: 32% (PCV13), 39% (PCV15), 65% (PCV20) and 69% (PPV23). Differences were found in serotype composition and antimicrobial resistance by age and type of infection. The maintenance of serotype 3 as a leading cause of adult pneumococcal pneumonia and the increase in highly invasive (serotype 8) or antimicrobial-resistant (serotype 11A) serotypes is worrisome. Further studies will be required to analyse the impact of the upcoming broader conjugate vaccines. | - |
dc.format.extent | 12 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI AG | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/microorganisms9112245 | - |
dc.relation.ispartof | Microorganisms, 2021, vol 9, num 11 | - |
dc.relation.uri | https://doi.org/10.3390/microorganisms9112245 | - |
dc.rights | cc by (c) Fernández Delgado, Lucía et al, 2021 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Pneumònia | - |
dc.subject.classification | Vacunes | - |
dc.subject.other | Pneumonia | - |
dc.subject.other | Vaccines | - |
dc.title | Serotypes in Adult Pneumococcal Pneumonia in Spain in the Era of Conjugate Vaccines | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2021-12-16T09:57:29Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 34835371 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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microorganisms-09-02245.pdf | 1.29 MB | Adobe PDF | View/Open |
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