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Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/182935
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dc.contributor.authorMaus, Mate-
dc.contributor.authorSerrano, Manuel-
dc.date.accessioned2022-02-04T16:54:15Z-
dc.date.available2022-09-21T05:10:21Z-
dc.date.issued2021-09-21-
dc.identifier.issn1097-4164-
dc.identifier.urihttp://hdl.handle.net/2445/182935-
dc.description.abstractIgelmann et al. report a novel metabolic cycle, which they name HTC, that converts NADH into the key antioxidant factor NADPH. The HTC is repressed by the tumor suppressors p53 and RB, and this determines whether oncogene-expressing cells undergo senescence (HTCoff) or malignant transformation (HTCon). Copyright © 2021 Elsevier Inc. All rights reserved.ca
dc.format.extent3 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoengca
dc.publisherElsevierca
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1016/j.molcel.2021.08.023-
dc.relation.ispartofMolecular Cell, 2021, vol 81, num 18, 3672-3674-
dc.relation.urihttps://doi.org/10.1016/j.molcel.2021.08.023-
dc.rightscc by-nc-nd (c) Elsevier, 2021-
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.sourceArticles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))-
dc.subject.classificationMetabolisme cel·lular-
dc.subject.classificationOncogens-
dc.subject.otherCell metabolism-
dc.subject.otherOncogenes-
dc.titleA novel redox cycle diverts cells from oncogene-induced senescence into cancerca
dc.typeinfo:eu-repo/semantics/articleca
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.date.updated2022-02-02T16:58:18Z-
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/669622/EU//CELLPLASTICITY-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.idimarina6533990-
dc.identifier.pmid34547231-
Appears in Collections:Publicacions de projectes de recerca finançats per la UE
Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))

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