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http://hdl.handle.net/2445/183062
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DC Field | Value | Language |
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dc.contributor.author | Santos García, Diego | - |
dc.contributor.author | Álvarez Sauco, Maria | - |
dc.contributor.author | Calopa, Matilde | - |
dc.contributor.author | Carrillo, Fátima | - |
dc.contributor.author | Escamilla Sevilla, Francisco | - |
dc.contributor.author | Freire, Eric | - |
dc.contributor.author | García Ramos, R. | - |
dc.contributor.author | Kulisevsky, Jaime | - |
dc.contributor.author | Gómez Esteban, Juan Carlos | - |
dc.contributor.author | Legarda, Inés | - |
dc.contributor.author | Luquín, María Rosario Isabel | - |
dc.contributor.author | Castrillo, Juan Carlos Martínez | - |
dc.contributor.author | Martínez Martin, Pablo | - |
dc.contributor.author | Martínez Torres, Irene | - |
dc.contributor.author | Mir, Pablo | - |
dc.contributor.author | Ignacio, Ángel Sesar | - |
dc.date.accessioned | 2022-02-11T16:21:40Z | - |
dc.date.available | 2022-02-11T16:21:40Z | - |
dc.date.issued | 2021-12-28 | - |
dc.identifier.issn | 2075-4418 | - |
dc.identifier.uri | http://hdl.handle.net/2445/183062 | - |
dc.description.abstract | Background and objective: Parkinson's disease (PD) is a clinically heterogeneous disorder in which the symptoms and prognosis can be very different among patients. We propose a new simple classification to identify key symptoms and staging in PD. Patients and Methods: Sixteen movement disorders specialists from Spain participated in this project. The classification was consensually approved after a discussion and review process from June to October 2021. The TNM classification and the National Institutes of Health Stroke Scale (NIHSS) were considered as models in the design. Results: The classification was named MNCD and included 4 major axes: (1) motor symptoms; (2) non-motor symptoms; (3) cognition; (4) dependency for activities of daily living (ADL). Motor axis included 4 sub-axes: (1) motor fluctuations; (2) dyskinesia; (3) axial symptoms; (4) tremor. Four other sub-axes were included in the non-motor axis: (1) neuropsychiatric symptoms; (2) autonomic dysfunction; (3) sleep disturbances and fatigue; (4) pain and sensory disorders. According to the MNCD, 5 stages were considered, from stage 1 (no disabling motor or non-motor symptoms with normal cognition and independency for ADL) to 5 (dementia and dependency for basic ADL). Conclusions: A new simple classification of PD is proposed. The MNCD classification includes 4 major axes and 5 stages to identify key symptoms and monitor the evolution of the disease in patients with PD. It is necessary to apply this proof of concept in a properly designed study. | - |
dc.format.extent | 14 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI AG | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/diagnostics12010055 | - |
dc.relation.ispartof | Diagnostics, 2021, vol 12, num 1 | - |
dc.relation.uri | https://doi.org/10.3390/diagnostics12010055 | - |
dc.rights | cc by (c) Santos García, Diego et al, 2021 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.source | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) | - |
dc.subject.classification | Malaltia de Parkinson | - |
dc.subject.classification | Manifestacions neurològiques de les malalties | - |
dc.subject.other | Parkinson's disease | - |
dc.subject.other | Neurologic manifestations of general diseases | - |
dc.title | MNCD: A New Tool for Classifying Parkinson’s Disease in Daily Clinical Practice | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2022-02-11T10:17:20Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 35054222 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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File | Description | Size | Format | |
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diagnostics-12-00055.pdf | 3.03 MB | Adobe PDF | View/Open |
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