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dc.contributor.authorFraser, Maya-
dc.contributor.authorMiller, John M.-
dc.contributor.authorSilumbe, Kafula-
dc.contributor.authorHainsworth, Michael-
dc.contributor.authorMudenda, Mutinta-
dc.contributor.authorHamainza, Busiko-
dc.contributor.authorMoonga, Hawela-
dc.contributor.authorChizema Kawesha, Elizabeth-
dc.contributor.authorMercer, Laina D.-
dc.contributor.authorBennett, Adam-
dc.contributor.authorSchneider, Kammerle-
dc.contributor.authorSlater, Hannah C.-
dc.contributor.authorEisele, Thomas P.-
dc.contributor.authorGuinovart, Caterina-
dc.description.abstractBACKGROUND NlmCategory: BACKGROUND content: In 2016, the Zambian National Malaria Elimination Centre started programmatic mass drug administration (pMDA) campaigns with dihydroartemisinin-piperaquine as a malaria elimination tool in Southern Province. Two rounds were administered, two months apart (coverage 70% and 57% respectively). We evaluated the impact of one year of pMDA on malaria incidence using routine data. - Label: METHODS NlmCategory: METHODS content: We conducted an interrupted time series with comparison group analysis on monthly incidence data collected at the health facility catchment area (HFCA) level, with a negative binomial model using generalized estimating equations. pMDA was conducted in HFCAs with greater than 50 cases/1,000 people/year. Ten HFCAs with incidence rates marginally above this threshold (pMDA group) were compared to 20 HFCAs marginally below (comparison group). - Label: RESULTS NlmCategory: RESULTS content: "The pMDA HFCAs saw a 46% greater decrease in incidence at the time of intervention than the comparison areas (incidence rate ratio: 0.536 [0.337-0.852]); however, incidence increased toward the end of the season. No HFCAs saw a transmission interruption." - Label: CONCLUSION NlmCategory: CONCLUSIONS content: pMDA, implemented during one year with imperfect coverage in low transmission areas with sub-optimal vector control coverage, significantly reduced incidence. However, elimination will require additional tools. Routine data are important resources for programmatic impact evaluations and should be considered for future analyses.-
dc.format.extent9 p.-
dc.publisherOxford University Press-
dc.relation.isformatofReproducció del document publicat a: 10.1093/infdis/jiaa434-
dc.relation.ispartofJournal of Infectious Diseases, 2021-
dc.relation.uri 10.1093/infdis/jiaa434-
dc.rightscc by (c) Fraser, Maya et al, 2021-
dc.subject.classificationPolítica sanitària-
dc.subject.otherMedical policy-
dc.titleEvaluating the impact of programmatic mass drug administration for malaria in Zambia using routine incidence data.-
Appears in Collections:Articles publicats en revistes (ISGlobal)

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