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http://hdl.handle.net/2445/183506
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DC Field | Value | Language |
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dc.contributor.author | Gaviria, Lorena Patrícia | - |
dc.contributor.author | Montsant, Lourdes | - |
dc.contributor.author | Azuaje, Carlos | - |
dc.contributor.author | González-Díaz, Aida | - |
dc.contributor.author | Horcajada Gallego, Juan Pablo | - |
dc.contributor.author | Limón, Enrique | - |
dc.contributor.author | Viñas, Miquel | - |
dc.contributor.author | Espinal, Paula | - |
dc.contributor.author | Fusté i Domínguez, Ester | - |
dc.date.accessioned | 2022-02-24T19:09:11Z | - |
dc.date.available | 2022-02-24T19:09:11Z | - |
dc.date.issued | 2022-02-18 | - |
dc.identifier.issn | 2076-2607 | - |
dc.identifier.uri | http://hdl.handle.net/2445/183506 | - |
dc.description.abstract | Urinary tract infections caused by extended-spectrum β-lactamase Escherichia coli (ESBLEC) are increasing worldwide and are a current concern because treatment options are often limited. This study investigated antimicrobial susceptibility, antimicrobial resistance genes (ARGs), and the biological diversity of urinary ESBL-EC isolates at Cerdanya Hospital, a European cross-border hospital that combines French and Spanish healthcare models. Bacterial identification and susceptibility were determined using the Microscan WalkAway® system and ESBL production was examined by the double-disk synergy method. Isolates were sequenced using the Ion S5¿ next-generation sequencing system, with the whole-genome sequences then assembled using SPADEs software and analyzed using PubMLST, ResFinder, FimTyper, PlasmidFinder, and VirulenceFinder. A phylogenetic analysis was performed by constructing an assembly-based core-SNV alignment, followed by a phylogenetic tree constructed using Parsnp from the Harvest suite. All isolates studied were multidrug-resistant and could be classified into 19 different sequence types characterized by a high genetic diversity. The most prevalent ESBL-enzymes were CTX-M-14 and CTX-M-15. High-risk international clones (ST131, ST10, and ST405) were also identified. The results demonstrated the absence of a single predominant clone of ESBL-MDR-EC at Cerdanya Hospital. | - |
dc.format.extent | 14 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/microorganisms10030488 | - |
dc.relation.ispartof | Microorganisms, 2022, vol. 10, p. 488 | - |
dc.relation.uri | https://doi.org/10.3390/microorganisms10030488 | - |
dc.rights | cc-by (c) Gaviria, Lorena Patrícia et al., 2022 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Infermeria de Salut Pública, Salut mental i Maternoinfantil) | - |
dc.subject.classification | Escheríchia coli | - |
dc.subject.classification | Infeccions del tracte urinari | - |
dc.subject.classification | Resistència als medicaments | - |
dc.subject.other | Escherichia coli | - |
dc.subject.other | Urinary tract infections | - |
dc.subject.other | Drug resistance | - |
dc.title | A descriptive analysis of urinary ESBL-Producing-Escherichia coli in Cerdanya Hospital | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 720167 | - |
dc.date.updated | 2022-02-24T19:09:11Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Infermeria de Salut Pública, Salut mental i Maternoinfantil) Articles publicats en revistes (Patologia i Terapèutica Experimental) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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720167.pdf | 1.45 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License