1. Dipòsit Digital de la Universitat de Barcelona
  2. Recerca
  3. Química Inorgànica i Orgànica
  4. Articles publicats en revistes (Química Inorgànica i Orgànica)
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/183770
Full metadata record
DC FieldValueLanguage
dc.contributor.authorMaga, Giovanni-
dc.contributor.authorRadi, Marco-
dc.contributor.authorZanoli, Samantha-
dc.contributor.authorManetti, Fabrizio-
dc.contributor.authorCancio, Reynel-
dc.contributor.authorHübscher, Ulrich-
dc.contributor.authorSpadari, Silvio-
dc.contributor.authorFalciani, Chiara-
dc.contributor.authorTerrazas Martínez, Montserrat-
dc.contributor.authorVilarrasa i Llorens, Jaume-
dc.contributor.authorBotta, Maurizio-
dc.date.accessioned2022-03-04T15:23:36Z-
dc.date.available2022-03-04T15:23:36Z-
dc.date.issued2007-
dc.identifier.issn1433-7851-
dc.identifier.urihttps://hdl.handle.net/2445/183770-
dc.description.abstractHow odd! A new class of non-nucleoside reverse transcriptase inhibitors with a 6-vinylpyrimidine scaffold (1) has been found to inhibit HIV-1 reverse transcriptase (RT) by competition with the nucleotide substrate after binding to the non-nucleoside inhibitor binding pocket of the enzyme. Molecular modeling studies have been performed to elucidate their peculiar behavior.-
dc.format.extent4 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherWiley-VCH-
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1002/anie.200604165-
dc.relation.ispartofAngewandte Chemie-International Edition, 2007, vol. 46, num. 11, p. 1810-1813-
dc.relation.urihttps://doi.org/10.1002/anie.200604165-
dc.rights(c) Wiley-VCH, 2007-
dc.sourceArticles publicats en revistes (Química Inorgànica i Orgànica)-
dc.subject.classificationNucleòsids-
dc.subject.classificationPirimidines-
dc.subject.classificationRadiocristal·lografia-
dc.subject.otherNucleosides-
dc.subject.otherPyrimidines-
dc.subject.otherX-ray crystallography-
dc.titleDiscovery of non-nucleoside inhibitors of HIV-1 reverse transcriptase competing with the nucleotide substrate-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/acceptedVersion-
dc.identifier.idgrec713452-
dc.date.updated2022-03-04T15:23:37Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
Appears in Collections:Articles publicats en revistes (Química Inorgànica i Orgànica)

Files in This Item:
File Description SizeFormat 
713452.pdf888.8 kBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.