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DC Field | Value | Language |
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dc.contributor.author | Panagopoulou, Maria | - |
dc.contributor.author | Esteller, Manel | - |
dc.contributor.author | Chatzaki, Ekaterini | - |
dc.date.accessioned | 2022-04-01T17:46:20Z | - |
dc.date.available | 2022-04-01T17:46:20Z | - |
dc.date.issued | 2021-02-10 | - |
dc.identifier.issn | 2072-6694 | - |
dc.identifier.uri | http://hdl.handle.net/2445/184630 | - |
dc.description.abstract | Breast cancer (BC) is a leading cause of death between women. Mortality is significantly raised due to drug resistance and metastasis, while personalized treatment options are obstructed by the limitations of conventional biopsy follow-up. Lately, research is focusing on circulating biomarkers as minimally invasive choices for diagnosis, prognosis and treatment monitoring. Circulating cell-free DNA (ccfDNA) is a promising liquid biopsy biomaterial of great potential as it is thought to mirror the tumor's lifespan; however, its clinical exploitation is burdened mainly by gaps in knowledge of its biology and specific characteristics. The current review aims to gather latest findings about the nature of ccfDNA and its multiple molecular and biological characteristics in breast cancer, covering basic and translational research and giving insights about its validity in a clinical setting. | - |
dc.format.extent | 25 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | MDPI | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/cancers13040728 | - |
dc.relation.ispartof | Cancers, 2021, vol. 13, num. 4, p. 728 | - |
dc.relation.uri | https://doi.org/10.3390/cancers13040728 | - |
dc.rights | cc-by (c) Panagopoulou, Maria et al., 2021 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Ciències Fisiològiques) | - |
dc.subject.classification | Càncer de mama | - |
dc.subject.classification | Pronòstic mèdic | - |
dc.subject.classification | ADN | - |
dc.subject.classification | Biòpsia | - |
dc.subject.classification | Marcadors bioquímics | - |
dc.subject.other | Breast cancer | - |
dc.subject.other | Prognosis | - |
dc.subject.other | DNA | - |
dc.subject.other | Biopsy | - |
dc.subject.other | Biochemical markers | - |
dc.title | Circulating cell-free DNA in breast cancer: searching for hidden information towards precision medicine | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 707516 | - |
dc.date.updated | 2022-04-01T17:46:21Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 33578793 | - |
Appears in Collections: | Articles publicats en revistes (Ciències Fisiològiques) |
Files in This Item:
File | Description | Size | Format | |
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707516.pdf | 1.18 MB | Adobe PDF | View/Open |
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