Por favor, use este identificador para citar o enlazar este documento: https://hdl.handle.net/2445/185792
Título: Consumption of caffeinated beverages and kidney function decline in an elderly Mediterranean population with metabolic syndrome
Autor: Díaz-López, Andrés
Paz Graniel, Indira
Ruiz, Verónica
Toledo Atucha, Estefanía
Becerra-Tomás, Nerea
Corella Piquer, Dolores
Castañer, Olga
Martínez, J. Alfredo, 1957-
Alonso-Gómez, Ángel M.
Wärnberg, Julia
Vioque, Jesús
Romaguera, Dora
López Miranda, José
Estruch Riba, Ramon
Tinahones, Francisco J.
Lapetra, José
Serra Majem, Lluís
Bueno Cavanillas, Aurora
Tur, Josep A.
Martín Sánchez, Vicente
Pintó Sala, Xavier
Delgado-Rodríguez, Miguel
Matía Martín, Pilar
Vidal i Cortada, Josep
Vázquez, Clotilde
Daimiel, Lidia
Villa, T.F.
Ros Rahola, Emilio
Eguaras, Sonia
Babio, Nancy
Sorlí, José V.
Goday Arnó, Albert
Abete, Itziar
Tojal Sierra, Lucas
Barón-López, Francisco Javier
Torres-Collado, Laura
Morey, Marga
Garcia-Rios, Antonio
Casas Rodríguez, Rosa M.
Bernal-López, Maria Rosa
Santos Lozano, José Manuel
Navarro, Adela
González, José I.
Zomeño Fajardo, María Dolores
Zulet, M. Angeles
Vaquero Luna, Jessica
Ramallal, Raul
Fitó Colomer, Montserrat
Salas Salvadó, Jordi
Materia: Cafeïna
Cafè (Beguda)
Síndrome metabòlica
Malalties del ronyó
Caffeine
Coffee drink
Metabolic syndrome
Kidney diseases
Fecha de publicación: 22-abr-2021
Publicado por: Nature Publishing Group
Resumen: It remains unclear whether caffeinated beverages could have deleterious renal effects in elderly population with underlying comorbid conditions. We investigated the associations between coffee, tea, or caffeine intake and 1-year changes in glomerular filtration rate (eGFR) in a large Spanish cohort of overweight/obese elderly with metabolic syndrome (MetS). This prospective analysis includes 5851 overweight/obese adults (55-75 years) with MetS from the PREDIMED-Plus study. We assessed coffee, tea, and caffeine consumption from a validated food-frequency questionnaire and creatinine-based eGFR using the Chronic Kidney Disease Epidemiology Collaboration equation. Multivariate-adjusted regression models were applied to test associations between baseline coffee, tea, or caffeine intake and 1-year eGFR changes. Caffeinated coffee (> 2 cups/day) and tea (at least 1 cup/day) drinkers had 0.88 and 0.93 mL/min/1.73 m2 greater eGFR decrease respectively, compared to those with less than 1 cup/day of coffee consumption or non-tea drinkers. Furthermore, caffeinated coffee consumption of > 2 cups/day was associated with 1.19-fold increased risk of rapid eGFR decline > 3 mL/min/1.73 m2 (95% CI 1.01-1.41). Similarly, individuals in the highest (median, 51.2 mg/day) tertile of caffeine intake had a 0.87 mL/min/1.73 m2 greater eGFR decrease. Decaffeinated coffee was not associated with eGFR changes. In conclusion, higher consumption of caffeinated coffee, tea, and caffeine was associated with a greater 1-year eGFR decline in overweight/obese adults with MetS.
Nota: Reproducció del document publicat a: https://doi.org/10.1038/s41598-021-88028-7
Es parte de: Scientific Reports, 2021, vol. 11, num. 1, p. 8719
URI: https://hdl.handle.net/2445/185792
Recurso relacionado: https://doi.org/10.1038/s41598-021-88028-7
ISSN: 2045-2322
Aparece en las colecciones:Articles publicats en revistes (Medicina)
Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
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