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Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/185901
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dc.contributor.authorMartínez Moreno, Rebecca-
dc.contributor.authorPérez Serra, Alexandra-
dc.contributor.authorCarreras, David-
dc.contributor.authorAran Corbella, Begoña-
dc.contributor.authorKuebler, Bernd-
dc.contributor.authorBrugada, Ramon-
dc.contributor.authorScornik, Fabiana S.-
dc.contributor.authorPérez, Guillermo J.-
dc.contributor.authorSelga i Coma, Elisabet-
dc.date.accessioned2022-05-23T08:32:08Z-
dc.date.available2022-05-23T08:32:08Z-
dc.date.issued2022-02-01-
dc.identifier.issn1873-5061-
dc.identifier.urihttp://hdl.handle.net/2445/185901-
dc.description.abstractThe effects of genetic mutations on protein function can be studied in a physiologically relevant environment using tissue-specific cells differentiated from patient-derived induced pluripotent stem cells (iPSC). However, it is crucial to use iPSC derived from healthy individuals as control. We generated an iPS cell line from skin fibroblasts of a healthy Caucasian male by nucleofection of non-integrating episomal vectors. This cell line has normal karyotype, expresses pluripotency surface markers and pluripotency genes, and successfully differentiates into cells of the 3 germ layers. Therefore, it can be used as control for any disease of interest that is modelled using iPSC.-
dc.format.extent5 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherElsevier-
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1016/j.scr.2022.102717-
dc.relation.ispartofStem Cell Research, 2022, vol. 60-
dc.relation.urihttps://doi.org/10.1016/j.scr.2022.102717-
dc.rightscc by-nc-nd (c) Martínez Moreno, Rebecca et al, 2022-
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.sourceArticles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))-
dc.subject.classificationFibroblasts-
dc.subject.classificationSistemes de control biològic-
dc.subject.otherFibroblasts-
dc.subject.otherBiological control systems-
dc.titleGeneration of an induced pluripotent stem cell line from a healthy Caucasian male-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.date.updated2022-05-19T08:08:41Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.pmid35231795-
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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