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http://hdl.handle.net/2445/186117
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DC Field | Value | Language |
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dc.contributor.author | Wendel Garcia, Pedro David | - |
dc.contributor.author | Mas, Arantxa | - |
dc.contributor.author | González Isern, Cristina | - |
dc.contributor.author | Ferrer Roca, Ricard | - |
dc.contributor.author | Máñez Mendiluce, Rafael | - |
dc.contributor.author | Masclans, Joan Ramon | - |
dc.contributor.author | Sandoval, Elena | - |
dc.contributor.author | Vera Artazcoz, Paula | - |
dc.contributor.author | Trenado Álvarez, José | - |
dc.contributor.author | Fernández, Rafael | - |
dc.contributor.author | Sirvent, Josep Maria | - |
dc.contributor.author | Martínez, Melcior | - |
dc.contributor.author | Ibarz, Mercedes | - |
dc.contributor.author | Garro, Pau | - |
dc.contributor.author | Lopera, José Luis | - |
dc.contributor.author | Bodí, María | - |
dc.contributor.author | Yébenes Reyes, Juan Carles | - |
dc.contributor.author | Triginer, Carles | - |
dc.contributor.author | Vallverdú, Imma | - |
dc.contributor.author | Baró, Anna | - |
dc.contributor.author | Bodí, Fernanda | - |
dc.contributor.author | Saludes, Paula | - |
dc.contributor.author | Valencia, Mauricio | - |
dc.contributor.author | Roche Campo, Ferran | - |
dc.contributor.author | Huerta, Arturo | - |
dc.contributor.author | Cambra Lasaosa, Francisco José | - |
dc.contributor.author | Barberà, Carme | - |
dc.contributor.author | Echevarria, Jorge | - |
dc.contributor.author | Peñuelas, Oscar | - |
dc.contributor.author | Mancebo, Jordi | - |
dc.contributor.author | UCIsCAT study group | - |
dc.date.accessioned | 2022-05-30T17:45:37Z | - |
dc.date.available | 2022-05-30T17:45:37Z | - |
dc.date.issued | 2022-02-08 | - |
dc.identifier.issn | 1364-8535 | - |
dc.identifier.uri | http://hdl.handle.net/2445/186117 | - |
dc.description.abstract | Background: Non-invasive oxygenation strategies have a prominent role in the treatment of acute hypoxemic respiratory failure during the coronavirus disease 2019 (COVID-19). While the efcacy of these therapies has been studied in hospitalized patients with COVID-19, the clinical outcomes associated with oxygen masks, high-fow oxy‑ gen therapy by nasal cannula and non-invasive mechanical ventilation in critically ill intensive care unit (ICU) patients remain unclear. Methods: In this retrospective study, we used the best of nine covariate balancing algorithms on all baseline covari‑ ates in critically ill COVID-19 patients supported with>10 L of supplemental oxygen at one of the 26 participating ICUs in Catalonia, Spain, between March 14 and April 15, 2020. Results: Of the 1093 non-invasively oxygenated patients at ICU admission treated with one of the three stand-alone non-invasive oxygenation strategies, 897 (82%) required endotracheal intubation and 310 (28%) died during the ICU stay. High-fow oxygen therapy by nasal cannula (n=439) and non-invasive mechanical ventilation (n=101) were associated with a lower rate of endotracheal intubation (70% and 88%, respectively) than oxygen masks (n=553 and 91% intubated), p<0.001. Compared to oxygen masks, high-fow oxygen therapy by nasal cannula was associated with lower ICU mortality (hazard ratio 0.75 [95% CI 0.58-0.98), and the hazard ratio for ICU mortality was 1.21 [95% CI 0.80-1.83] for non-invasive mechanical ventilation. Conclusion: In critically ill COVID-19 ICU patients and, in the absence of conclusive data, high-fow oxygen therapy by nasal cannula may be the approach of choice as the primary non-invasive oxygenation support strategy | - |
dc.format.extent | 13 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | BioMed Central | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1186/s13054-022-03905-5 | - |
dc.relation.ispartof | Critical Care, 2022, vol. 26, num. 1, p. 37 | - |
dc.relation.uri | https://doi.org/10.1186/s13054-022-03905-5 | - |
dc.rights | cc-by (c) Wendel Garcia, Pedro David et al., 2022 | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | COVID-19 | - |
dc.subject.classification | Síndrome del destret respiratori de l'adult | - |
dc.subject.classification | Unitats de cures intensives | - |
dc.subject.classification | Oxigenoteràpia | - |
dc.subject.classification | Teràpia respiratòria | - |
dc.subject.classification | Nas | - |
dc.subject.other | COVID-19 | - |
dc.subject.other | Adult respiratory distress syndrome | - |
dc.subject.other | Intensive care units | - |
dc.subject.other | Oxygen therapy | - |
dc.subject.other | Respiratory therapy | - |
dc.subject.other | Nose | - |
dc.title | Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 718789 | - |
dc.date.updated | 2022-05-30T17:45:37Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 35135588 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) |
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718789.pdf | 1.43 MB | Adobe PDF | View/Open |
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