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http://hdl.handle.net/2445/186940
Title: | Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018 |
Author: | Parrón Bernabé, Ignacio Barrabeig i Fabregat, Irene Alseda, Miquel Rius, Cristina Cornejo Sánchez, Thais Jané, Mireia Pérez, Cristina Guix Arnau, Susana Domínguez García, Àngela |
Keywords: | Gastroenteritis Serveis de cures de llarga durada Vellesa Gastroenteritis Long-term care facilities Old age |
Issue Date: | 1-Dec-2021 |
Publisher: | Nature Publishing Group |
Abstract: | Norovirus is the leading cause of outbreaks of acute viral gastroenteritis. We carried out this study to investigate outbreaks in long-term care facilities reported in 2017 and 2018 in Catalonia (Spain). The characteristics of the centers, exposed persons and the genogroups responsible were analyzed. Viral loads were estimated. The attack rate (AR) of the outbreaks studied, and the rate ratio (RR) and the odds ratio (OR) and their 95% confdence intervals as measures of association were calculated. The mean cycle thresholds were compared using the t-test for independent means. We included 30 outbreaks (4631 exposed people). The global AR was 25.93%. The RR of residents vs. staf was 2.28 (95% CI 2.0-2.6). The RR between AR in residents with total or severe dependence vs. residents with moderate, low or no-dependence was 1.23 (95% CI 1.05-1.45). The AR were higher in smaller centers than in larger ones (38.47% vs. 19.25% and RR 2; 95% CI 1.82-2.2). GII was responsible for 70% of outbreaks. No association was found between the genogroup and presenting symptoms (OR 0.96; 95% CI 0.41-2.26). Viral loads were higher in symptomatic than in asymptomatic patients (p = 0.001). |
Note: | Reproducció del document publicat a: https://doi.org/10.1038/s41598-021-02348-2 |
It is part of: | Scientific Reports, 2021, vol. 11, p. 23218 |
URI: | http://hdl.handle.net/2445/186940 |
Related resource: | https://doi.org/10.1038/s41598-021-02348-2 |
ISSN: | 2045-2322 |
Appears in Collections: | Articles publicats en revistes (Medicina) |
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